Protein Information

Name CXCR4
Synonyms C X C chemokine receptor type 4; LAP 3; LAP3; Seven transmembrane helix receptor; NPYR; CD184; CD184 antigen; CXC R4…

Compound Information

Name chlordecone
CAS

Reference List

PubMed Abstract RScore(About this table)
17578864 Wang F, Roberts SM, Butfiloski EJ, Morel L, Sobel ES: Acceleration of autoimmunity by organochlorine pesticides: a comparison of splenic B-cell effects of chlordecone and estradiol in (NZBxNZW) F1 mice. Toxicol Sci. 2007 Sep;99(1):141-52. Epub 2007 Jun 19.

Both chlordecone and E2 activated splenic B cells and enhanced GC reactions, as shown by upregulated protein expression of GL7, CXCR5, and CXCR4.
31(0,1,1,1) Details