---

chlordecone

Identification (Source:EPA,EU)

ID	1475
Name	chlordecone
CAS	143-50-0
IUPAC
Inchi	InChI=1S/C10Cl10O/c11-2-1(21)3(12)6(15)4(2,13)8(17)5(2,14)7(3,16)9(6,18)10(8,19)20
CIPAC	297
EPA Code	027701
Formula	C10Cl10O
SMILES	ClC54C(=O)C1(Cl)C2(Cl)C5(Cl)C3(Cl)C4(Cl)C1(Cl)C2(Cl)C3(Cl)Cl
Status	Not Approved

Classification

Mode of Action	Central nervous system stimulant. GABA-gated chloride channel antagonist.
Pesticide Type	Insecticide, Fungicide, Metabolite
Chemical Group	Organochlorine
Classification	cyclodiene insecticides

Properties (Source:PubChem)

Molecular Weight	490.64
Physical State	Tan to white coloured solid depending upon purity
AlogP	4.638
H-Bond Donor	0
H-Bond Acceptor	1
Surface Area	333.76
Polar Surface Area	17.07

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.27 mg l-1
Aquatic crustaceans	Acute	96 hour	LC50	0.010 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.03 mg l-1
Aquatic invertebrates	Chronic	21 day	NOEC	0.011 mg l-1
Birds	Acute		LD50	237 mg kg-1
Earthworms	Acute	14 day	LD50	105 mg kg-1
Fish	Acute	96 hour	LC50	0.02 mg l-1
Mammals	Acute oral		LD50	91.3 mg kg-1
	Bio-concentration factor		BCF	60000

Related targets

Target Name	RScore (About this table)
ATPases	1149(12,16,24,29)	Details
ATPase	926(8,14,25,51)	Details
estrogen receptor	851(8,12,16,71)	Details
calmodulin	369(4,4,10,19)	Details
cytochrome P450 (protein family or complex)	294(2,4,12,34)	Details
progesterone receptor	250(2,4,7,15)	Details
Met enkephalin	227(2,3,8,12)	Details
adenylate cyclase	202(2,3,3,12)	Details
GC B	163(2,2,2,3)	Details
brains	152(1,3,4,7)	Details
beta endorphin	100(1,1,4,5)	Details
aldo keto reductase (protein family or complex)	98(1,1,1,18)	Details
ornithine decarboxylase	92(1,1,2,7)	Details
CD4	87(1,1,2,2)	Details
beta glucuronidase	82(1,1,1,2)	Details
thymidine kinase	82(1,1,1,2)	Details
acetylcholine receptor (protein family or complex)	81(1,1,1,1)	Details
CXCR5	81(1,1,1,1)	Details
serotonin receptors (protein family or complex)	43(0,1,3,3)	Details
CCL4	43(0,1,3,3)	Details
Lactoferrin	40(0,1,2,5)	Details
phosphodiesterase	38(0,1,1,8)	Details
serotonin receptor	37(0,1,2,2)	Details
pregnane X receptor	32(0,1,1,2)	Details
bcl 2	32(0,1,1,2)	Details
alpha adrenergic receptor (protein family or complex)	31(0,1,1,1)	Details
MC 2	31(0,1,1,1)	Details
CXCR4	31(0,1,1,1)	Details
5 HT1A	31(0,1,1,1)	Details
chlordecone reductase	40(0,0,0,40)	Details

Docunmentation of Network Visuallization