| Name | ATPases |
|---|---|
| Synonyms | (NA+ + K+)ATPase; ATP1A1; ATPase; ATPase Na+/K+ transporting alpha 1 polypeptide; Na (+) K (+) ATPase; Na (+),K (+) ATPase; Na + K + ATPase; Na K + ATPase… |
| Name | chlordecone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 6196030 | Chetty SC, Aldous CN, Rashatwar SS, Desaiah D: Effect of chlordecone on pH and temperature dependent substrate activation kinetics of rat brain synaptosomal ATPases. Biochem Pharmacol. 1983 Nov 1;32(21):3205-11. |
311(3,5,6,6) | Details |
| 6158768 | Desaiah D, Gilliland T, Ho IK, Mehendale HM: Inhibition of mouse brain synaptosomal ATPases and ouabain binding by chlordecone. Toxicol Lett. 1980 Sep;6(4-5):275-85. |
255(3,3,5,5) | Details |
| 6175765 | Desaiah D: Interaction of chlordecone with biological membranes. . J Toxicol Environ Health. 1981 Nov-Dec;8(5-6):719-30. An attempt is made in this paper to review the effects of chlordecone on the membrane-bound adenosinetriphosphatases (ATPases) and related phenomena. |
250(3,3,4,5) | Details |
| 2471839 | Jinna RR, Uzodinma JE, Desaiah D: Age-related changes in rat brain ATPases during treatment with chlordecone. J Toxicol Environ Health. 1989;27(2):199-208. Mg2+-ATPases were inhibited in both in vitro and in vivo treatment with chlordecone. |
88(1,1,2,3) | Details |
| 2413407 | Bansal SK, Desaiah D: Chlordecone toxicity: effect of withdrawal of treatment on ATPase inhibition. Neurotoxicology. 1985 Fall;6(3):103-7. Rats treated with chlordecone for 10 days showed a significant reduction of Na+-K+ ATPase activity in brain and kidney. |
88(1,1,2,3) | Details |
| 2845111 | Kodavanti PR, Mehrotra BD, Chetty SC, Desaiah D: Effect of selected insecticides on rat brain synaptosomal adenylate cyclase and phosphodiesterase. J Toxicol Environ Health. 1988;25(2):207-15. Previous reports from our laboratory and others clearly indicated that organochlorine insecticides such as chlordecone and DDT are potent inhibitors of ATPases involved in active ion transport. |
82(1,1,1,2) | Details |
| 6160190 | Desaiah D: Comparative effects of chlordecone and mirex on rat cardiac ATPases and binding of 3H-catecholamines. J Environ Pathol Toxicol. 1980 Aug;4(1):237-48. |
62(0,2,2,2) | Details |
| 6172757 | Jordan JE, Grice T, Mishra SK, Desaiah D: Acute chlordecone toxicity in rats: a relationship between tremor and ATPase activities. Neurotoxicology. 1981 Oct;2(2):355-64. For biochemical study chlordecone treated rats were killed, the brain synaptosomes were prepared and Na+-K+ ATPase, oligomycin-sensitive and insensitive Mg2+ ATPases were determined. |
12(0,0,2,2) | Details |
| 1701552 | Kodavanti PR, Cameron JA, Yallapragada PR, Desaiah D: Effect of chlordecone (Kepone) on transport mechanisms in rat heart sarcoplasmic reticulum. Pharmacol Toxicol. 1990 Sep;67(3):227-34. In agreement with this, both high affinity and low affinity Ca2 (+)-ATPases, which are involved in Ca2+ transport across membranes, were also inhibited by CD in a concentration dependent manner with IC50 values of 0.7 and 3.2 microM respectively. |
1(0,0,0,1) | Details |