| Name | Lactoferrin |
|---|---|
| Synonyms | GIG12; Growth inhibiting protein 12; HLF 2; HLF2; LF; LTF; Lactoferrin; Lactotransferrin… |
| Name | chlordecone |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9607801 | Das SK, Tan J, Johnson DC, Dey SK: Differential spatiotemporal regulation of lactoferrin and progesterone receptor genes in the mouse uterus by primary and xenoestrogen. Endocrinology. 1998 Jun;139(6):2905-15. To examine this further, we compared the effects of estrogenic (o,p'-DDT [1-(o-chlorophenyl)-1-(p-chlorophenyl) 2,2,2-trichloroethane] and Kepone, chlordecone) and nonestrogenic (p,p'-DDD [1,1-dichloro-2,2-bis (p-chlorophenyl) ethane], a metabolite of p,p'-DDT) xenobiotics with those of 17beta- (E2) and 4-hydroxyestradiol-17beta (4-OH-E2), a metabolite of E2, on uterine expression of lactoferrin (LF) and progesterone receptor (PR). |
32(0,1,1,2) | Details |
| 9371753 | Das SK, Taylor JA, Korach KS, Paria BC, Dey SK, Lubahn DB: Estrogenic responses in estrogen receptor-alpha deficient mice reveal a distinct signaling pathway. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12786-91. By using ER-alpha "knock-out" (ERKO) mice, we demonstrate herein that a catecholestrogen, 4-hydroxyestradiol-17beta (4-OH-E2), and an environmental chlordecone (kepone), up-regulate the uterine expression of an -responsive gene, lactoferrin (LF), independent of ER-alpha. |
6(0,0,1,1) | Details |
| 10828501 | Mehmood Z, Smith AG, Tucker MJ, Chuzel F, Carmichael NG: The development of methods for assessing the in vivo oestrogen-like effects of xenobiotics in CD-1 mice. Food Chem Toxicol. 2000 Jun;38(6):493-501. The chemicals investigated were: bisphenol A (1 g/kg body weight/day), (1 g/kg body weight/day) o,p'-DDT (500 mg/kg body weight/day), (1 g/kg/day), coumestrol (0.5 mg/kg/day) and chlordecone (20 mg/kg/day) administered subcutaneously daily for 3 days. These were, in addition to the commonly measured changes in relative uterus weight and histopathological examination of uterine tissue, three other markers indicative of uterotrophic effects, namely, uterine luminal epithelium BrdU labelling index over the last 24 hr, peroxidase activity and lactoferrin expression. |
2(0,0,0,2) | Details |