Name | bcl 2 |
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Synonyms | Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas… |
Name | chlordecone |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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18951962 | Wang F, Sobel ES, Butfiloski EJ, Roberts SM: Comparison of chlordecone and effects on splenic T-cells in (NZBxNZW) F (1) mice. Toxicol Lett. 2008 Dec 15;183(1-3):1-9. Epub 2008 Sep 18. On the other hand, both chlordecone and E2 increased Bcl-2 expression in CD4 T-cells and reduced CD4 T-cell apoptosis without affecting their proliferation. |
31(0,1,1,1) | Details |
17578864 | Wang F, Roberts SM, Butfiloski EJ, Morel L, Sobel ES: Acceleration of autoimmunity by organochlorine pesticides: a comparison of splenic B-cell effects of chlordecone and in (NZBxNZW) F1 mice. Toxicol Sci. 2007 Sep;99(1):141-52. Epub 2007 Jun 19. Both treatments increased B-cell bcl-2 and shp-1 gene expression and enhanced ICAM-1 and VCAM-1 protein levels in GC B cells. |
1(0,0,0,1) | Details |