Protein Information

Name lactate dehydrogenase (protein family or complex)
Synonyms LDH; lactate dehydrogenase; lactate dehydrogenases

Compound Information

Name fenitrothion
CAS

Reference List

PubMed Abstract RScore(About this table)
10928684 Srivastava AK, Malik JK: Effect of diacetylmonoxime on blood enzymes in fenitrothion-dosed buffalo calves. Vet Hum Toxicol. 2000 Aug;42(4):212-5.

Fenitrothion given po at 435 mg/kg bw produced pronounced inhibition of blood acetylcholinesterase (AChE) and elevation in serum aspartate and alanine aminotransferases, acid and alkaline phosphatases, and lactate dehydrogenase within 30 min.
82(1,1,1,2) Details
516603 Bogatykh TA, Orlova NV, Kuznetsova TV: [Activity of lactate dehydrogenase and glucose-6-phosphate dehydrogenase activity in rat testicular tissues after exposure to certain pesticides]. Vopr Pitan. 1979 Sep-Oct;(5):49-53.

3(0,0,0,3) Details
3927568 Nistiar F, Hrusovsky J, Mojzis J: [The effect of dichlorvos and metathion on selected enzymes of the amoeba Tetrahymena pyriformis]. Vet Med. 1985 Jul;30(7):443-7.


Dichlorvos was studied for its action at supratoxic doses (50.0, 100.0 and 150.0 mg per litre) and it was found that lactate dehydrogenase activity was almost completely suppressed; the inhibition of alanine aminotransferase was pronounced.
1(0,0,0,1) Details
6829035 Reddy PS, Bhagyalakshmi A, Ramamurthi R: Chronic sumithion toxicity: effect on carbohydrate metabolism in crab muscle. Toxicol Lett. 1983 Feb;15(2-3):113-7.


The enzymes concerned with glycogenolytic metabolism (phosphorylase), glycolytic metabolism (aldolase), aerobic metabolism [succinate dehydrogenase (SDH), malate dehydrogenase (MDH)], anaerobic metabolism, lactate dehydrogenase (LDH) and alanine amino transaminase (AIAT)], were assayed in the muscle of control and experimental crabs.
1(0,0,0,1) Details
20214973 El-Shenawy NS: Effects of insecticides fenitrothion, endosulfan and abamectin on antioxidant parameters of isolated rat hepatocytes. Toxicol In Vitro. 2010 Mar 7.

Increased leakage percentage of lactate dehydrogenase (LDH), alanine transaminase (ALT) and aspartate aminotranferase (AST) were detected in hepatocytes due to the same dose of insecticide exposure confirmed membrane damage of hepatocytes.
1(0,0,0,1) Details