| PubMed |
Abstract |
RScore(About this table) |
| 12527698 |
Kitamura S, Suzuki T, Kadota T, Yoshida M, Ohashi K, Ohta S: In vitro metabolism of fenthion and fenthion sulfoxide by liver preparations of sea bream, goldfish, and rats. Drug Metab Dispos. 2003 Feb;31(2):179-86.
Fenthion sulfoxide was reduced to fenthion with liver cytosol of the fish and rats upon addition of 2-hydroxypyrimidine, N (1)-methylnicotinamide, or butyraldehyde, each of which is an electron donor of aldehyde oxidase, under anaerobic conditions. |
39(0,1,2,4) |
Details |
| 18845175 |
Leoni C, Buratti FM, Testai E: The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion. Toxicol Appl Pharmacol. 2008 Dec 1;233(2):343-52. Epub 2008 Sep 19.
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7(0,0,1,2) |
Details |
| 12676606 |
Kitamura S, Suzuki T, Ohta S, Fujimoto N: Antiandrogenic activity and metabolism of the organophosphorus pesticide fenthion and related compounds. Environ Health Perspect. 2003 Apr;111(4):503-8.
However, when fenthion sulfoxide was incubated with liver cytosol in the presence of 2-hydroxypyrimidine, an electron donor of aldehyde oxidase, the extract of the incubation mixture exhibited antiandrogenic activity. |
6(0,0,1,1) |
Details |