| Name | androgen receptor |
|---|---|
| Synonyms | AIS; AR; Androgen receptor; DHTR; Dihydrotestosterone receptor; HUMARA; KD; NR3C4… |
| Name | fenvalerate |
|---|---|
| CAS | cyano(3-phenoxyphenyl)methyl 4-chloro-α-(1-methylethyl)benzeneacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2325407 | Eil C, Nisula BC: The binding properties of pyrethroids to human skin fibroblast androgen receptors and to sex hormone binding globulin. J Steroid Biochem. 1990 Mar;35(3-4):409-14. All the pyrethroids tested inhibited fibroblast binding of [3H] methyltrienolone (R1881) at 22 degrees C with the following rank order of potency:pyrethrins greater than bioallethrin greater than fenvalerate greater than fenothrin greater than fluvalinate greater than permethrin greater than resmethrin. 50% displacement of [3H] R1881 binding to fibroblast androgen receptors was achieved by 1.5-44 x 10 (-5) M concentrations of the competitors, respectively. |
84(1,1,1,4) | Details |
| 16857237 | Sun H, Xu XL, Xu LC, Song L, Hong X, Chen JF, Cui LB, Wang XR: Antiandrogenic activity of pyrethroid pesticides and their metabolite in reporter gene assay. Chemosphere. 2007 Jan;66(3):474-9. Epub 2006 Jul 20. We tested three frequently encountered pyrethroids (fenvalerate, cypermethrin, permethrin) and their metabolite 3-phenoxybenzoic acid (3-PBA) for antiandrogenic and androgenic activity using a human androgen receptor (AR) mediated luciferase reporter gene assay in CV-1 African green monkey kidney cell. |
81(1,1,1,1) | Details |
| 12052007 | Kunimatsu T, Yamada T, Ose K, Sunami O, Kamita Y, Okuno Y, Seki T, Nakatsuka I: Lack of (anti-) androgenic or estrogenic effects of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) in the Hershberger and uterotrophic assays. Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 1):227-37. In the present study, we evaluated the interaction of three pyrethroids (esfenvalerate, fenvalerate, and permethrin) with androgen receptor (AR)- and estrogen receptor (ER)-mediated mechanisms using in vivo short-term assays. |
81(1,1,1,1) | Details |
| 16125883 | Xu LC, Sun H, Chen JF, Bian Q, Song L, Wang XR: Androgen receptor activities of p,p'-DDE, fenvalerate and phoxim detected by androgen receptor reporter gene assay. Toxicol Lett. 2006 Jan 5;160(2):151-7. Epub 2005 Aug 25. |
8(0,0,1,3) | Details |