Protein Information

Name demethylase
Synonyms DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases…

Compound Information

Name fipronil
CAS

Reference List

PubMed Abstract RScore(About this table)
18767755 Fang Q, Huang CH, Ye GY, Yao HW, Cheng JA, Akhtar ZR: Differential fipronil susceptibility and metabolism in two rice stem borers from China. J Econ Entomol. 2008 Aug;101(4):1415-20.

The susceptibilities of larvae of two rice stem borers, namely, Chilo suppressalis (Walker) (Lepidoptera: Crambidae) and Sesamia inferens (Walker) (Lepidoptera: Nocutidae) to fipronil and its metabolites were investigated, and then the activities of microsomal O-demethylase, and glutathione transferase (GST) in two species were measured.
82(1,1,1,2) Details
12192904 Durham EW, Siegfried BD, Scharf ME: In vivo and in vitro metabolism of fipronil by larvae of the European corn borer Ostrinia nubilalis. Pest Manag Sci. 2002 Aug;58(8):799-804.

Cytochrome P450-dependent monooxygenase activity (methoxyresorufin O-demethylase) was consistently observed in midgut preparations, and formation and detection of the sulfone metabolite in the same midgut preparations was also NADPH-dependent and inhibited by piperonyl butoxide.
1(0,0,0,1) Details