| Name | Ah receptor |
|---|---|
| Synonyms | AHR; Ah receptor; AhR; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; Dioxin receptor; Ah receptors; AhRs… |
| Name | diflubenzuron |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16411658 | Jiang H, Vudathala DK, Blair IA, Penning TM: Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo [a] pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction. Chem Res Toxicol. 2006 Jan;19(1):68-78. P4501B1 induction was blocked in AKR1A1 transfectants by the AKR1A1 inhibitor (sulfonylnitromethane), the o- scavenger (N-acetyl- or the cytosolic AhR antagonist (diflubenzuron). |
32(0,1,1,2) | Details |
| 10799337 | Ledirac N, Delescluse C, Lesca P, Piechocki MP, Hines RN, de Sousa G, Pralavorio M, Rahmani R: Diflubenzuron, a benzoyl-urea insecticide, is a potent inhibitor of TCDD-induced CYP1A1 expression in HepG2 cells. Toxicol Appl Pharmacol. 2000 May 1;164(3):273-9. Finally, in competitive binding studies using a 9S-enriched fraction of HepG2 cytosol, DFB was capable of displacing [(3) H]-2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) from its Ah receptor binding site. |
2(0,0,0,2) | Details |
| 9820645 | Delescluse C, Ledirac N, de Sousa G, Pralavorio M, Lesca P, Rahmani R: Cytotoxic effects and induction of cytochromes P450 1A1/2 by insecticides, in hepatic or epidermal cells: binding capability to the Ah receptor. Toxicol Lett. 1998 Aug;96-97:33-9. We therefore tested the comparative acute and chronic toxicity of chemicals belonging to the major insecticides families (DDT, malathion and tetrachlorvinphos, carbaryl, cypermethrin, diflubenzuron), in hepatocytes, HepG2 and HaCaT cell lines. |
1(0,0,0,1) | Details |