Protein Information

Name CYP2D6
Synonyms CPD 6; Xenobiotic monooxygenase; Microsomal monooxygenase; Flavoprotein linked monooxygenase; CPD6; CYP2D; CYP2D variant; CYP2D6…

Compound Information

Name diuron
CAS

Reference List

PubMed Abstract RScore(About this table)
17576805 Abass K, Reponen P, Turpeinen M, Jalonen J, Pelkonen O: Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes. Drug Metab Dispos. 2007 Sep;35(9):1634-41. Epub 2007 Jun 18.

All tested recombinant human cytochrome P450s (P450s) catalyzed diuron N-demethylation and the highest activities were possessed by CYP1A1, CYP1A2, CYP2C19, and CYP2D6.
81(1,1,1,1) Details