Protein Information

Name IL 1beta
Synonyms Catabolin; IL 1; IL 1 beta; IL 1B; IL1 beta; IL1B; IL1F2; Interleukin 1…

Compound Information

Name sulfur
CAS sulfur

Reference List

PubMed Abstract RScore(About this table)
19651324 Kehe K, Balszuweit F, Steinritz D, Thiermann H: Molecular toxicology of sulfur mustard-induced cutaneous inflammation and blistering. Toxicology. 2009 Sep 1;263(1):12-9. Epub 2009 Jan 23.

Additionally, SM upregulates many inflammatory mediators including interleukin (IL)-1alpha, IL-1beta, IL-6, IL-8, tumor necrosis factor-alpha (TNF-alpha) and others.
1(0,0,0,1) Details
19733693 Amiri S, Ghazanfari T, Yaraee R, Salimi H, Ebtekar M, Shams J, Ghasemi H, Pourfarzam S, Moin A, Sharifnia Z, Soroush MR, Faghihzadeh S, Hassan ZM: Serum levels of GM-CSF 20 years after sulfur mustard exposure: Sardasht-Iran Cohort Study. Int Immunopharmacol. 2009 Dec;9(13-14):1499-503. Epub 2009 Sep 4.

Moreover, positive correlations were found between circulating levels of GM-CSF with IL-1alpha, IL-1beta, TNF-alpha and IL-6.
1(0,0,0,1) Details
19572781 Wigenstam E, Rocksen D, Ekstrand-Hammarstrom B, Bucht A: Treatment with dexamethasone or liposome-encapsuled vitamin E provides beneficial effects after chemical-induced lung injury. Inhal Toxicol. 2009 Sep;21(11):958-64.

The pathogenesis of lung injury by exposure to highly toxic sulfur and nitrogen mustards involves alkylating damage of the respiratory epithelium followed by an acute inflammatory response and lung edema.
A single intraperitoneal injection of dexamethasone (10 mg/kg body weight) 1 hour after melphalan exposure significantly reduced interleukin (IL)-1 and IL-6 in bronchoalveolar lavage fluid (BALF) and diminished the acute airway inflammation.
1(0,0,0,1) Details
19747989 Yaraee R, Ghazanfari T, Ebtekar M, Ardestani SK, Rezaei A, Kariminia A, Faghihzadeh S, Mostafaie A, Vaez-Mahdavi MR, Mahmoudi M, Naghizadeh MM, Soroush MR, Hassan ZM: Alterations in serum levels of inflammatory cytokines (TNF, IL-1alpha, IL-1beta and IL-1Ra) 20 years after sulfur mustard exposure: Sardasht-Iran cohort study. Int Immunopharmacol. 2009 Dec;9(13-14):1466-70. Epub 2009 Sep 11.
10(0,0,1,5) Details
19847372 Huang XL, Zhou JL, Zhou XH, Xian XH, Ding CH: [Ameliorative effects of exogenous sulfur dioxide on lipopolysaccharide-induced acute lung injury in rats.]. Sheng Li Xue Bao. 2009 Oct 25;61(5):499-503.

The number of polymorphonuclear neutrophil (PMN) in the bronchoalveolar lavage fluid (BALF), intercellular adhesion factor-1 (ICAM-1) expression in the lung tissue and IL-1, IL-6 and IL-10 levels in the serum were tested.
3(0,0,0,3) Details
19776584 Lee JS, Kwon KA, Jung HS, Kim JH, Hahm KB: Korea red ginseng on Helicobacter pylori-induced halitosis: newer therapeutic strategy and a plausible mechanism. Digestion. 2009;80(3):192-9. Epub 2009 Sep 16.

BACKGROUND: Gas chromatographic documentation of volatile sulfur compounds in Helicobacter pylori cultures and the amelioration of halitosis after eradication suggested a causal link between H. pylori infection and halitosis.
The expressions of cystathionine gamma-lyase (CSE), cystathionine beta-synthetase (CBS), IL-6, IL-8 and IL-1beta mRNA were compared in H. pylori-infected or NaHS-treated gastric epithelial cells according to red ginseng treatment.
2(0,0,0,2) Details
19733692 Ghasemi H, Ghazanfari T, Yaraee R, Ghassemi-Broumand M, Soroush MR, Pourfarzam S, Masdari Z, Faghihzadeh S, Babaei M, Javadi MA, Kiuchi Y, Naghizadeh MM, Owlia P, Hassan ZM: Evaluation of relationship between the serum levels of inflammatory mediators and ocular injuries induced by sulfur mustard: Sardasht-Iran Cohort Study. Int Immunopharmacol. 2009 Dec;9(13-14):1494-8. Epub 2009 Sep 4.

The serum levels of IL-1beta in the exposed group with Slit lamp findings were significantly lower than their counterpart in the control group.
2(0,0,0,2) Details