| Name | demethylase |
|---|---|
| Synonyms | DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases… |
| Name | flusilazole |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2679371 | Trzaskos JM, Henry MJ: Comparative effects of the azole-based fungicide flusilazole on yeast and mammalian 14 alpha-methyl demethylase. Antimicrob Agents Chemother. 1989 Aug;33(8):1228-31. |
6(0,0,1,1) | Details |
| 8302930 | Doignon F, Aigle M, Ribereau-Gayon P: Resistance to imidazoles and triazoles in Saccharomyces cerevisiae as a new dominant marker. Plasmid. 1993 Nov;30(3):224-33. The and triazole fungicides inhibit cytochrome P450 14 alpha- demethylase (P45014DM) implicated in the biosynthesis pathway, which is specific to fungi and yeasts. |
3(0,0,0,3) | Details |
| 15554355 | Trosken ER, Scholz K, Lutz RW, Volkel W, Zarn JA, Lutz WK: Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans. Endocr Res. 2004 Aug;30(3):387-94. Antifungal activity is based on inhibition of fungal CYP51 14alpha-demethylase), and biosynthesis reduction is due to azole inhibition of CYP19 (aromatase). Most potent fungicides included prochloraz, flusilazole, and imazalil, and most potent medicinal antifungals were bifonazole, miconazole, and |
1(0,0,0,1) | Details |
| 7773307 | Grausem B, Chaubet N, Gigot C, Loper JC, Benveniste P: Functional expression of Saccharomyces cerevisiae CYP51A1 encoding lanosterol-14-demethylase in tobacco results in bypass of endogenous sterol biosynthetic pathway and resistance to an -14-demethylase herbicide inhibitor. Plant J. 1995 May;7(5):761-70. However, these transgenic calli were killed by mixtures of gamma-kt plus fungicide inhibitors of LAN14DM such as ketoconazole, itraconazole or flusilazole which alone were not effective. |
2(0,0,0,2) | Details |