Protein Information

Name IL 8
Synonyms 3 10C; AMCF I; CXC chemokine ligand 8; CXCL 8; CXCL8; Emoctakin; GCP 1; GCP1…

Compound Information

Name formaldehyde
CAS formaldehyde

Reference List

PubMed Abstract RScore(About this table)
19086277 Choi CH, Kim TI, Lee SK, Yang KM, Kim WH: Effect of Lactobacillus GG and conditioned media on IL-1beta-induced IL-8 production in Caco-2 cells. Scand J Gastroenterol. 2008 Aug;43(8):938-47.

To determine the nature of the immunomodulatory molecules, the LGG was modified to the following: treated with antibiotics, 4% formaldehyde, incubation at 95 degrees C, or sonication.
8(0,0,0,8) Details
17520822 Zhang LL, Lu J, Yu SQ, He JL, Zhou M, Xu GL: [Protective effect of rupatadine against oleic acid-induced acute lung injury in rabbits]. Yao Xue Xue Bao. 2007 Mar;42(3):252-6.

Shortly after the rabbits were killed at 3 hour after iv OA injection, bronchoalveolar lavage fluid (BALF) was colleted, and the concentrations of protein, platelet-activating factor (PAF), intercellular adhesion molecule-1 (ICAM-1), interleukin 8 (IL-8) in BALF were then measured by ELISA.
Lung tissue was fixed in formaldehyde and stained with HE, and examined under a light microscope.
2(0,0,0,2) Details
17969629 Dehlink E, Domig KJ, Loibichler C, Kampl E, Eiwegger T, Georgopoulos A, Kneifel W, Urbanek R, Szepfalusi Z: Heat- and formalin-inactivated probiotic bacteria induce comparable cytokine patterns in intestinal epithelial cell-leucocyte cocultures. J Food Prot. 2007 Oct;70(10):2417-21.


To further investigate the influence of inactivation treatment on cytokine production, three probiotic strains were evaluated-live, heat-inactivated, and formalin-inactivated strains-for their impact on interleukin (IL) 6, IL-8, and IL-10 production in Caco-2-leucocyte cocultures.
2(0,0,0,2) Details
19240301 Feng CY, Johnson SC, Hori TS, Rise M, Hall JR, Gamperl AK, Hubert S, Kimball J, Bowman S, Rise ML: Identification and analysis of differentially expressed genes in immune tissues of Atlantic cod stimulated with formalin-killed, atypical Aeromonas salmonicida. Physiol Genomics. 2009 May 13;37(3):149-63. Epub 2009 Feb 24.


Genes confirmed by QPCR as upregulated by A. salmonicida included interleukin-1 beta, interleukin-8, a small inducible cytokine, interferon regulatory factor 1 (IRF1), ferritin heavy subunit, cathelicidin, and hepcidin.
1(0,0,0,1) Details
18939936 Curt S, Subirade M, Rouabhia M: Production and in vitro evaluation of soy protein-based biofilms as a support for human keratinocyte and fibroblast culture. Tissue Eng Part A. 2009 Jun;15(6):1223-32.

This was supported by the high level of messenger RNA expression of interleukin-1 beta (IL-1beta) and tumor necrosis factor alpha by the keratinocytes and of IL-6 and IL-8 by the fibroblasts.
SPI biofilms were prepared from SPI chemically treated with formaldehyde at various concentrations (0%, 1%, 2%, and 3%) as cross-linking agents.
1(0,0,0,1) Details