Name | c jun |
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Synonyms | AP1; Activator protein 1; JUN; Proto oncogene c jun; Protooncogene c jun; Transcription factor AP 1; V jun avian sarcoma virus 17 oncogene homolog; c Jun… |
Name | benzalkonium chloride |
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CAS | quaternary ammonium compounds, alkylbenzyldimethyl, chlorides |
PubMed | Abstract | RScore(About this table) | |
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12603851 | Aiba S, Manome H, Nakagawa S, Mollah ZU, Mizuashi M, Ohtani T, Yoshino Y, Tagami H: p38 Mitogen-activated protein kinase and extracellular signal-regulated kinases play distinct roles in the activation of dendritic cells by two representative haptens, NiCl2 and 2,4-dinitrochlorobenzene. J Invest Dermatol. 2003 Mar;120(3):390-9. Human monocyte-derived dendritic cells stimulated with 2,4-dinitrochlorobenzene induced the phosphorylation of p38 and stress-activated protein kinase/c-jun N-terminal kinases, whereas NiCl2 induced that of p44/42 extracellular signal-regulated kinases, p38, and stress-activated protein kinase/c-jun N-terminal kinases. In contrast, primary irritants, e.g., benzalkonium chloride, or did not activate these signal transduction pathways. |
1(0,0,0,1) | Details |
17881916 | Okada Y: Effects of topical antiglaucoma medications on corneal epithelium as evaluated by gene expression patterns. Cornea. 2007 Oct;26(9 Suppl 1):S46-54. PURPOSE: To examine the expression pattern of the stress-related genes c-fos and c-jun, which encode the 2 major components of activator protein (AP)-1, and cyclooxygenase (COX)-2 in rat corneal epithelium treated with topical antiglaucoma medications and benzalkonium chloride (BAK) preservative. |
36(0,1,1,6) | Details |
9211828 | Parr EJ, Sharkey KA: Multiple mechanisms contribute to myenteric plexus ablation induced by benzalkonium chloride in the guinea-pig ileum. Cell Tissue Res. 1997 Aug;289(2):253-64. We examined the effects of this detergent on neurons and glia, including expression of c-Myc, c-Jun, JunB, and c-Fos, and on immunocytes in the guinea-pig ileum. |
2(0,0,0,2) | Details |