| Name | epidermal growth factor receptor |
|---|---|
| Synonyms | EGF receptor; EGFR; EGFR protein; ERBB; ERBB 1; ERBB1; Epidermal growth factor receptor; Epidermal growth factor receptor isoform a variant… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14661455 | Sun MY, Liu BL, Jing YG, Yang C, Shang HT, Li JH: [Influence of different temperatures on internalization of epidermal growth factor receptor complexes in Tca-8113 cells]. Shanghai Kou Qiang Yi Xue. 2003 Feb;12(1):18-20. |
164(2,2,2,4) | Details |
| 19448409 | Jiang JG, Shen GF, Chen C, Fu XN, Wang DW: Effects of cytochrome P450 arachidonic acid epoxygenases on the proliferation of tumor cells. Ai Zheng. 2009 Jan;28(1):14-9. Epub 2009 Jan 5. METHODS: The effects of recombinant adeno-associated virus (rAAV) mediated cytochrome P450 2J2 (CYP2J2), cytochrome P450 F87V (CYPF87V) and anti-CYP2J2 on proliferation of Tca-8113, A549, Ncl-H446 and HepG2 cells were measured using MTT and flow cytometry. Expressions of phosphorylated epidermal growth factor receptor (EGFR), extracellular signal-regulated kinase (ERK) 1/2 and Akt before and after transfection were detected by western blot. |
3(0,0,0,3) | Details |
| 16317705 | Dent P, Fang Y, Gupta S, Studer E, Mitchell C, Spiegel S, Hylemon PB: Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes. Hepatology. 2005 Dec;42(6):1291-9. (DCA), (CDCA), (TDCA), (GDCA), (TCDCA), (GCDCA), (TCA), (GCA), and all activated ERK1/2 in primary rat hepatocytes that was abolished by inhibition of ERBB1, and significantly reduced by ROS quenching agents. |
3(0,0,0,3) | Details |
| 12865235 | Wang XW, Zhang JR, Shen Y, Zheng G, Zhong CC: Glivec enhances the down-regulated cytotoxicity of adriamycin in acquired tamoxifen-resistant MCF-7 cell line. Di Yi Jun Yi Da Xue Xue Bao. 2003 Jul;23(7):731-3. OBJECTIVE: To study the alteration of bax, bcl-2, p170 expressing and the second effect on the adriamycin (ADR) induced cytotoxicity in acquired tamoxifen (TAM)-resistant MCF-7 cell line. |
4(0,0,0,4) | Details |
| 15560844 | Knight LA, Di Nicolantonio F, Whitehouse P, Mercer S, Sharma S, Glaysher S, Johnson P, Cree IA: The in vitro effect of gefitinib ('Iressa') alone and in combination with cytotoxic chemotherapy on human solid tumours. BMC Cancer. 2004 Nov 23;4:83. BACKGROUND: Activation of the epidermal growth factor receptor (EGFR) triggers downstream signaling pathways that regulate many cellular processes involved in tumour survival and growth. |
2(0,0,0,2) | Details |
| 15280219 | Takada T, Weiss HM, Kretz O, Gross G, Sugiyama Y: Hepatic transport of PKI166, an epidermal growth factor receptor kinase inhibitor of the pyrrolo-pyrimidine class, and its main metabolite, ACU154. Drug Metab Dispos. 2004 Nov;32(11):1272-8. Epub 2004 Jul 27. |
2(0,0,0,2) | Details |
| 15363585 | Laughter AR, Dunn CS, Swanson CL, Howroyd P, Cattley RC, Corton JC: Role of the peroxisome proliferator-activated receptor alpha (PPARalpha) in responses to trichloroethylene and metabolites, trichloroacetate and dichloroacetate in mouse liver. Toxicology. 2004 Oct 15;203(1-3):83-98. Transcript profiling using macroarrays containing approximately 1200 genes showed that 93% (40 out of 43) of all expression changes observed in wild-type mice upon TCE exposure were dependent on PPARalpha and included known targets of PP (Cyp4a12, epidermal growth factor receptor) and additional genes involved in cell growth. |
1(0,0,0,1) | Details |