Protein Information

Name AP 1 (protein family or complex)
Synonyms AP 1; AP 1 complex; AP1; Adapter related protein complex 1

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
18603277 Karagiannidis AI, Bader AG, Hartl M, Bister K: TOJ3, a v-jun target with intrinsic oncogenic potential, is directly regulated by Jun via a novel AP-1 binding motif. Virology. 2008 Sep 1;378(2):371-6. Epub 2008 Jul 7.

4(0,0,0,4) Details
14673133 Manna PR, Eubank DW, Stocco DM: Assessment of the role of activator protein-1 on transcription of the mouse steroidogenic acute regulatory protein gene. Mol Endocrinol. 2004 Mar;18(3):558-73. Epub 2003 Dec 12.


Among these CRE elements, the CRE2 half-site is analogous (TGACTGA) to an activator protein-1 (AP-1) sequence [TGA (C/G) TCA]; therefore, the role of the AP-1 transcription factor was explored in StAR gene transcription.
7(0,0,0,7) Details
19298531 Chen DD, Dong YG, Liu D, He JG: Epigallocatechin-3-gallate attenuates cardiac hypertrophy partly via MAPKs signals in hypertensive rats. Clin Exp Pharmacol Physiol. 2009 Mar 2.


The phosphorylations of ERK2, p38, and JNK1 were significantly increased in left ventricle of EGCG treated TCA rats, accompanied with activations of NF-kappaB and AP-1.
1(0,0,0,1) Details