Name | caspase 3 |
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Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
Name | TCA |
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CAS | 2,2,2-trichloroacetic acid |
PubMed | Abstract | RScore(About this table) | |
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16055945 | Levkovitz Y, Gil-Ad I, Zeldich E, Dayag M, Weizman A: Differential induction of apoptosis by antidepressants in glioma and neuroblastoma cell lines: evidence for p-c-Jun, cytochrome c, and caspase-3 involvement. J Mol Neurosci. 2005;27(1):29-42. |
3(0,0,0,3) | Details |
16481486 | Walker DH, Yu XJ: Progress in rickettsial genome analysis from pioneering of Rickettsia prowazekii to the recent Rickettsia typhi. Ann N Y Acad Sci. 2005 Dec;1063:13-25. The genome of R. typhi contains four potentially membranolytic genes (tlyA, tlyC, pldA, and pat-1) and five autotransporter genes, sca 1, sca 2, sca 3, ompA, and ompB. |
1(0,0,0,1) | Details |
18094529 | Choi YJ, Uhm SJ, Song SJ, Song H, Park JK, Kim T, Park C, Kim JH: Cytochrome c upregulation during capacitation and spontaneous acrosome reaction determines the fate of pig sperm cells: linking proteome analysis. J Reprod Dev. 2008 Feb;54(1):68-83. Epub 2007 Dec 18. During induction, cytochrome c expression via the p53 pathway increased, however apoptotic executors, such as caspase-3, decreased significantly. |
1(0,0,0,1) | Details |
15965072 | Huang HM, Ou HC, Chen HL, Hou RC, Jeng KC: Protective effect of hypoxia or oxidative stress. Ann N Y Acad Sci. 2005 May;1042:272-8. KMV also reduced caspase-3 and -9 activation under stress. |
on BV-2 microglia under 1(0,0,0,1) | Details |
19289568 | Chen C, Li G, Liao W, Wu J, Liu L, Ma D, Zhou J, Elbekai RH, Edin ML, Zeldin DC, Wang DW: Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo. J Pharmacol Exp Ther. 2009 Jun;329(3):908-18. Epub 2009 Mar 16. In Tca-8113 cells, the CYP2J2 inhibitors decreased EET production by approximately 60%, whereas they had no effect on CYP2J2 mRNA or protein expression. Inhibition of CYP2J2 also significantly potentiated human tumor cell apoptosis and caused a corresponding increase in caspase-3 activity and change in expression of apoptosis-related proteins Bax and Bcl-2. |
1(0,0,0,1) | Details |
20300697 | Ruan M, Yan M, Yang WJ, Qu XZ, Zhou XJ, Chen WT, Zhang CP: [Role of NF-kappaB pathway in shikonin induced apoptosis in oral squamous cell carcinoma Tca-8113 cells.]. Shanghai Kou Qiang Yi Xue. 2010 Feb;19(1):66-71. METHODS: Expression of IkappaBa, phosphatase-IkappaBa, bcl-2 and Bax proteins were detected by Western blot, NF-kappaB DNA-binding activity was detected by electrophoretic mobility shift analysis (EMSA), and activities of caspase 3, caspase 8 and caspase 9 were analyzed by enzyme linked immunosorbent assay (ELISA). |
1(0,0,0,1) | Details |