| Name | somatostatin |
|---|---|
| Synonyms | Growth hormone release inhibiting factor; SMST; SST; Somatostatin; Somatostatin precursor; Somatostatins; Somatostatin precursors |
| Name | benzalkonium chloride |
|---|---|
| CAS | quaternary ammonium compounds, alkylbenzyldimethyl, chlorides |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12452385 | Sobreira LF, Zucoloto S, Garcia SB, Troncon LE: Effects of myenteric denervation on gastric epithelial cells and gastric emptying. Dig Dis Sci. 2002 Nov;47(11):2493-9. After benzalkonium chloride treatment, there was significant delay in gastric emptying of liquids and an increase in mucosal area of all gastric portions, in antral mucosal volume, in parietal cell area, and gastrin-G cell and somatostatin-D cell populations. |
7(0,0,1,2) | Details |
| 2434341 | Fox DA, Herman JR, Bass P: Differentiation between myenteric plexus and longitudinal muscle of the rat jejunum as the site of action of putative enteric neurotransmitters. Eur J Pharmacol. 1986 Nov 12;131(1):39-47. The myenteric plexus of a segment of rat jejunum was destroyed by serosal application of benzalkonium chloride (BAC). Fifteen days after BAC treatment, both the BAC-treated and an orad control jejunal segment were removed and the mechanical responses of the longitudinal muscle produced by the following substances were examined: substance P, cholecystokinin octapeptide (CCK-8), vasoactive intestinal peptide (VIP), bombesin, [Leu5] enkephalin and somatostatin. |
1(0,0,0,1) | Details |
| 9288684 | Higham A, Noble P, Thompson DG, Dockray GJ: Increased sensitivity of gastrin cells to gastric distension following antral denervation in the rat. J Physiol. 1997 Aug 15;503 ( Pt 1):169-75. We have examined the relative importance of luminal and neuronal mechanisms, by lesioning the antral innervation using benzalkonium chloride. 2. Plasma gastrin was measured by radioimmunoassay and mRNAs encoding gastrin, somatostatin and histidine decarboxylase were measured by Northern blot. 3. |
2(0,0,0,2) | Details |
| 2419771 | Piotrowski W, Foreman JC: On the actions of substance P, somatostatin, and vasoactive intestinal polypeptide on rat peritoneal mast cells and in human skin. Naunyn Schmiedebergs Arch Pharmacol. 1985 Dec;331(4):364-8. The release of induced by these neuropeptides was inhibited by preincubation of the cells with the SP analogue [D-Pro4,D-Trp7,9,10]-SP4-11 (SP-A) (10 microM), and also by benzalkonium chloride (10 microM). |
2(0,0,0,2) | Details |
| 3233640 | Zucoloto S, Diaz JA, Oliveira JS, Muccilo G, Sales Neto VN, Kajiwara JK: Effect of chemical ablation of myenteric neurones on intestinal cell proliferation. Cell Tissue Kinet. 1988 Jul;21(4):213-9. These changes are probably induced by functional imbalance by the surviving neuronal elements in the gut, implicating neurotransmitters such as somatostatin and vasoactive intestinal peptide. The duodenum or descending colon of male Wistar rats (average weight 60 g) was treated by a serosal application of a 0.2% solution of benzalkonium chloride (BAC) for 30 min. |
1(0,0,0,1) | Details |
| 6195330 | Fox DA, Epstein ML, Bass P: Surfactants selectively ablate enteric neurons of the rat jejunum. . J Pharmacol Exp Ther. 1983 Nov;227(2):538-44. Various concentrations of the cationic surfactants benzalkonium chloride (BAC) and benzethonium the anionic surfactants ricinoleate, dioctyl sulfosuccinate and and the nonionic surfactant Triton X-100 were applied to the serosal surface of the rat jejunum every 5 min for 0.5 hr and then rinsed off with saline. BAC treatment markedly reduced the immunoreactivity of somatostatin, substance P, met-enkephalin and vasoactive intestinal peptide in the myenteric plexus. |
1(0,0,0,1) | Details |