Protein Information

Name Urokinase type plasminogen activator
Synonyms ATF; PLAU; PLAU protein; Plasminogen activator urinary; Plasminogen activator urokinase; U plasminogen activator; UPA; URK…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
16356605 Wang J, Guo F, Wei H, Dong J, Wu J: Expression of urokinase-type plasminogen activator receptor is correlated with metastases of lingual squamous cell carcinoma. Br J Oral Maxillofac Surg. 2006 Dec;44(6):515-9. Epub 2005 Dec 13.

In this study we used reverse transcription polymerase chain reaction, immunocytochemistry, and Western-blot to examine the expression of uPAR mRNA and protein in Ts and Tca 8113 cell lines of lingual squamous cell carcinoma and in normal oral mucosal cells. uPAR mRNA and protein were expressed in Ts cells, but not in Tca 8113 cells or in normal oral epithelial cells.
3(0,0,0,3) Details
12177171 Huang W, Ishii I, Zhang WY, Sonobe M, Kruth HS: PMA activation of macrophages alters macrophage metabolism of aggregated LDL. J Lipid Res. 2002 Aug;43(8):1275-82.


The serum factor that mediated aggregated LDL release and disaggregation was plasmin generated from plasminogen by macrophage urokinase plasminogen activator.
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20337899 Phan TC, Ooi J, Goonewardene MS: A novel molecule, SLURP-1, enhances the survival of periodontal ligament fibroblasts. J Periodontal Res. 2010 Mar 9.


The aim of this study was to examine the role of a novel molecule, secreted mammalian Ly-6/urokinase-type plasminogen activator receptor-related protein 1 (SLURP-1), in periodontal ligament fibroblast survival.
1(0,0,0,1) Details