Name | HERG |
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Synonyms | HERG; Voltage gated potassium channel; ERG; ERG1; Eag homolog; Eag related protein 1; Ether a go go related gene potassium channel 1; Ether a go go related protein 1… |
Name | TCA |
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CAS | 2,2,2-trichloroacetic acid |
PubMed | Abstract | RScore(About this table) | |
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18458880 | Scherer D, von Lowenstern K, Zitron E, Scholz EP, Bloehs R, Kathofer S, Thomas D, Bauer A, Katus HA, Karle CA, Kiesecker C: Inhibition of cardiac hERG channels by tetracyclic antidepressant mianserin. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jul;378(1):73-83. Epub 2008 May 6. HERG channels were expressed in the Xenopus oocyte expression system and in human embryonic kidney (HEK) cells and currents were measured with two-microelectrode voltage-clamp and whole-cell patch-clamp, respectively. |
3(0,0,0,3) | Details |
20210726 | Alvarez PA, Pahissa J: QT alterations in psychopharmacology: proven candidates and suspects. Curr Drug Saf. 2010 Jan;5(1):97-104. Blockage of Human ether-a-go-go-related gene (HERG) potassium channel by psychoactive drugs appears to be related to this adverse effect. |
1(0,0,0,1) | Details |
19814705 | Alvarez PA, Pahissa J: QT Alterations in Psychopharmacology: Proven Candidates and Suspects. Curr Drug Saf. 2009 Oct 7. Blockage of Human ether-a-go-go-related gene (HERG) potassium channel by psychoactive drugs appears to be related to this adverse effect. |
1(0,0,0,1) | Details |