Protein Information

Name PPARdelta
Synonyms FAAR; NR1C2; NUC 1; NUC1; NUCI; NUCII; Nuclear hormone receptor 1; PPAR beta…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
19968882 Roberts LD, Hassall DG, Winegar DA, Haselden JN, Nicholls AW, Griffin JL: Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor delta from Peroxisome proliferator-activated receptor gamma in the ob/ob mouse. Genome Med. 2009 Dec 7;1(12):115.

7(0,0,0,7) Details
17726146 Jucker BM, Yang D, Casey WM, Olzinski AR, Williams C, Lenhard SC, Legos JJ, Hawk CT, Sarkar SK, Newsholme SJ: Selective PPARdelta agonist treatment increases skeletal muscle lipid metabolism without altering mitochondrial energy coupling: an in vivo magnetic resonance spectroscopy study. Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1256-64. Epub 2007 Aug 28.

In separate experiments where mitochondrial coupling was assessed in vivo (day 7), (31) P-MRS was used to measure hindlimb ATP synthesis and (13) C-MRS was used to measure the hindlimb tricarboxylic acid cycle flux (V (tca)).
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