Protein Information

Name glucose 6 phosphatase
Synonyms G 6 Pase; G6PC; G6PT; G6Pase; GSD1a; Glucose 6 phosphatase; Glucose 6 phosphatase hydrolytic subunit; G6Pases…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
12841626 Malarkodi KP, Balachandar AV, Varalakshmi P: The influence of lipoic acid on adriamycin induced nephrotoxicity in rats. Mol Cell Biochem. 2003 May;247(1-2):15-22.


The gluconeogenic enzymes, glucose-6-phosphatase and fructose-1,6-diphosphatase, showed a decline in their activities on adriamycin administration.
1(0,0,0,1) Details
19340598 Kumar V, Sahu NP, Pal AK, Kumar S, Sinha AK, Ranjan J, Baruah K: Modulation of key enzymes of glycolysis, gluconeogenesis, amino acid catabolism, and TCA cycle of the tropical freshwater fish Labeo rohita fed gelatinized and non-gelatinized starch diet. Fish Physiol Biochem. 2009 Apr 2.


A 60-day experiment was conducted to study the effect of dietary gelatinized (G) and non-gelatinized (NG) starch on the key metabolic enzymes of glycolysis (hexokinase, glucokinase, pyruvate kinase, and lactate dehydrogenase), gluconeogenesis (glucose-6 phosphatase and fructose-1,6 bisphosphatase), protein metabolism (aspartate amino transferase and alanine amino transferase), and TCA cycle (malate dehydrogenase) in Labeo rohita juveniles.
2(0,0,0,2) Details
20305288 Cao R, Cronk ZX, Zha W, Sun L, Wang X, Fang Y, Studer E, Zhou H, Pandak WM, Dent P, Gil G, Hylemon PB: Bile acids regulate hepatic gluconeogenic genes and FXR via G-alpha-i protein coupled receptor (s) and the AKT pathway. J Lipid Res. 2010 Mar 20.


In the current study, the chronic bile fistula (CBF) rat model and primary rat hepatocytes (PRH) were used to study the regulation of gluconeogenic genes (PEPCK and G-6-Pase) and the gene encoding short heterodimeric partner (SHP) by taurocholate (TCA).
2(0,0,0,2) Details
14604472 Arathi G, Sachdanandam P: Therapeutic effect of Semecarpus anacardium Linn. nut milk extract on carbohydrate metabolizing and mitochondrial TCA cycle and respiratory chain enzymes in mammary carcinoma rats. J Pharm Pharmacol. 2003 Sep;55(9):1283-90.


Mammary carcinoma-bearing rats showed a significant rise in glycolytic enzymes (hexokinase, phosphoglucoisomerase and aldolase) and a simultaneous fall in gluconeogenic enzymes (glucose-6-phosphatase and fructose 1,6-diphosphatase).
2(0,0,0,2) Details