| Name | tumor necrosis factor alpha |
|---|---|
| Synonyms | Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17072339 | Starczynowski DT, Trautmann H, Pott C, Harder L, Arnold N, Africa JA, Leeman JR, Siebert R, Gilmore TD: Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity. Oncogene. 2007 Apr 26;26(19):2685-94. Epub 2006 Oct 30. The S525P mutation reduces IKKalpha- and tumor necrosis factor (TNF) alpha-stimulated transactivation by a GAL4-REL protein. |
1(0,0,0,1) | Details |
| 16389718 | Ruetsch O, Viala A, Bardou H, Martin P, Vacheron MN: [Psychotropic drugs induced weight gain: a review of the literature concerning epidemiological data, mechanisms and management]. Encephale. 2005 Jul-Aug;31(4 Pt 1):507-16. According to current concepts, appetite and feeding are regulated by a complex of neurotransmitters, neuromodulators, cytokines and hormones interacting with the hypothalamus, including the leptin and the tumor necrosis factor system. |
1(0,0,0,1) | Details |
| 15450858 | Hassoun EA, Kini V: Effects of superoxide dismutase and polyclonal tumor necrosis factor-alpha antibodies on chloroacetate-induced cellular death and production by J774.A1 macrophages. Comp Biochem Physiol C Toxicol Pharmacol. 2004 Jun;138(2):113-20. |
2(0,0,0,2) | Details |
| 18383346 | Gavillet M, Allaman I, Magistretti PJ: Modulation of astrocytic metabolic phenotype by proinflammatory cytokines. Glia. 2008 Jul;56(9):975-89. In previous experiments, we showed that long-term treatment with interleukin 1alpha (IL-1alpha) or tumor necrosis factor-alpha (TNFalpha) alone increases utilization in primary culture of mouse astrocytes. |
2(0,0,0,2) | Details |
| 12609461 | Dredge K, Connor TJ, Kelly JP, Leonard BE: Differential effect of a single high dose of the tricyclic antidepressant on interleukin-1beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats. Int J Immunopharmacol. 1999 Oct;21(10):663-73. |
2(0,0,0,2) | Details |
| 17380379 | Beretti F, Cenacchi V, Portolani M, Ardizzoni A, Blasi E, Cermelli C: A transmissible cytotoxic activity isolated from a patient with brain ischemia causes microglial cell activation and dysfunction. Cell Mol Neurobiol. 2007 Jun;27(4):517-28. Epub 2007 Mar 23. Moreover, TCA-treated cells produced amounts of macrophage inflammatory protein 1-alpha, tumor necrosis factor-alpha, and significantly higher than mock-treated cells. |
1(0,0,0,1) | Details |
| 15822568 | Toribio RE, Kohn CW, Hardy J, Rosol TJ: Alterations in serum parathyroid hormone and electrolyte concentrations and urinary excretion of electrolytes in horses with induced endotoxemia. J Vet Intern Med. 2005 Mar-Apr;19(2):223-31. The goal of this study was to determine the effect of endotoxin (lipopolysaccharide [LPS]) administration to healthy horses on serum parathyroid hormone (PTH), ionized (Ca2+) and total (tCa), ionized (Mg2+) and total (tMg), (Pi), (K+), (Na+), (Cl-), and insulin concentrations, and on the urinary excretion of these electrolytes. In LPS-infused horses, heart rate increased significantly from (mean +/- SD) 40.0 +/- 1.3 to 70.0 +/- 9.0 beats/min, respiratory rate from 12.7 +/- 1.0 to 21.1 +/- 3.0 breaths/min, body temperature from 37.4 +/- 0.3 to 38.9 +/- 0.6 degrees C, and tumor necrosis factor-alpha concentrations from 6.6 +/- 3.5 to 507 +/- 260 pg/mL (P < .05). |
1(0,0,0,1) | Details |