Protein Information

Name chemokines
Synonyms CXCL12; Chemokine; Chemokine ligand 12; PBSF; Pre B cell growth stimulating factor; SCYB12; SDF 1 alpha; SDF 1 beta…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
12828562 Glabinski AR, Bielecki B, Ransohoff RM: Chemokine upregulation follows cytokine expression in chronic relapsing experimental autoimmune encephalomyelitis. Scand J Immunol. 2003 Jul;58(1):81-8.

7(0,0,0,7) Details
16274458 Renninger ML, Seymour R, Lillard JW Jr, Sundberg JP, HogenEsch H: Increased expression of chemokines in the skin of chronic proliferative dermatitis mutant mice. Exp Dermatol. 2005 Dec;14(12):906-13.

5(0,0,0,5) Details
16891627 Fenton JI, Hursting SD, Perkins SN, Hord NG: Leptin induces an Apc genotype-associated colon epithelial cell chemokine production pattern associated with macrophage chemotaxis and activation. Carcinogenesis. 2007 Feb;28(2):455-64. Epub 2006 Aug 4.

5(0,0,0,5) Details
17164723 Xie JF, Wang G, Debonera F, Han R, Dorf ME, Hancock W, Olthoff KM: Selective neutralization of the chemokine TCA3 reduces the increased injury of partial versus whole liver transplants induced by cold preservation. Transplantation. 2006 Dec 15;82(11):1501-9.

5(0,0,0,5) Details
15494499 Singh UP, Singh S, Ravichandran P, Taub DD, Lillard JW Jr: Viral macrophage-inflammatory protein-II: a viral chemokine that differentially affects adaptive mucosal immunity compared with its mammalian counterparts. J Immunol. 2004 Nov 1;173(9):5509-16.

5(0,0,0,5) Details
18594181 Lee SK, Choi BK, Kang WJ, Kim YH, Park HY, Kim KH, Kwon BS: MCP-1 derived from stromal keratocyte induces corneal infiltration of CD4+ T cells in herpetic stromal keratitis. Mol Cells. 2008 Jul 31;26(1):67-73. Epub 2008 Jul 2.


We hypothesized that chemokines produced by stromal keratocytes are involved in CD4 (+) T cell infiltration into the cornea.
3(0,0,0,3) Details
17196668 Brod SA, Hood Z: Ingested (oral) SIRS peptide 1-21 inhibits acute EAE by inducing Th2-like cytokines. J Neuroimmunol. 2007 Feb;183(1-2):89-95. Epub 2006 Dec 29.


Splenocytes from SIRS peptide 1-21 fed mice showed increased production of Th2-like CD30L, IL-13, TCA-3 cytokines/chemokines and decreased production of Th1-like cytokine lymphotactin.
2(0,0,0,2) Details
18226543 Sauder C, Pedras-Vasconcelos J, Puig M, Verthelyi D: The IP10 (CXCL10) specific cDNA probe of the mCK-5c multiprobe RNase protection assay kit carries two nucleotide insertions that complicate the interpretation of results. Cytokine. 2008 Feb;41(2):182-6. Epub 2008 Jan 15.


We used BD Biosciences/Pharmingen's mouse chemokine probeset mCK-5c to measure chemokine gene expression in brain and spleen tissue of mice.
1(0,0,0,1) Details
18940934 Wiener Z, Pocza P, Racz M, Nagy G, Tolgyesi G, Molnar V, Jaeger J, Buzas E, Gorbe E, Papp Z, Rigo J, Falus A: IL-18 induces a marked gene expression profile change and increased Ccl1 (I-309) production in mouse mucosal mast cell homologs. Int Immunol. 2008 Dec;20(12):1565-73. Epub 2008 Oct 21.


DNA microarray technology uncovered a group of chemokines regulated by IL-18, among which Ccl1 (I-309, TCA-3) showed the highest up-regulation.
1(0,0,0,1) Details
15145609 Mi W, Belyavskyi M, Johnson RR, Sieve AN, Storts R, Meagher MW, Welsh CJ: Alterations in chemokine expression following Theiler's virus infection and restraint stress. J Neuroimmunol. 2004 Jun;151(1-2):103-15.

1(0,0,0,1) Details