| Name | aspartate aminotransferase |
|---|---|
| Synonyms | Aspartate Aminotransferase 1; GIG18; GOT 1; GOT1; Aspartate aminotransferase; Glutamate oxaloacetate transaminase 1; Transaminase A; Aspartate aminotransferases… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12119542 | Madej M, Lundh T, Lindberg JE: Activity of enzymes involved in energy production in the small intestine during suckling-weaning transition of pigs. Biol Neonate. 2002;82(1):53-60. The activity of citrate synthase, isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, dehydrogenase, alanine aminotransferase and aspartate aminotransferase was determined in the small intestine epithelium of piglets during suckling-weaning transition. |
4(0,0,0,4) | Details |
| 19768502 | Soderberg MA, Cianciotto NP: Mediators of lipid A modification, RNA degradation, and central intermediary metabolism facilitate the growth of Legionella pneumophila at low temperatures. Curr Microbiol. 2010 Jan;60(1):59-65. Epub 2009 Sep 19. The proteins thereby implicated in low-temperature growth included components of the type II secretion system (LspE, LspG, LspH), a lipid A biosynthetic enzyme (LpxP), a ribonuclease (RNAse R), an RNA helicase (CsdA/DeaD), TCA cycle enzymes (citrate synthase), enzymes linked to fatty acid (FadB) or amino acid (aspartate aminotransferase) catabolism, and two putative membrane proteins that were, based upon their sequences, unlike previously characterized proteins. |
2(0,0,0,2) | Details |
| 18593602 | Frick NT, Bystriansky JS, Ip YK, Chew SF, Ballantyne JS: Carbohydrate and amino acid metabolism in fasting and aestivating African lungfish (Protopterus dolloi). Comp Biochem Physiol A Mol Integr Physiol. 2008 Sep;151(1):85-92. Epub 2008 Jun 14. The increase in dehydrogenase (GDH) and aspartate aminotransferase (Asp-AT) activities in the liver of aestivating P. dolloi suggests some energy may be obtained via increased aminoacid catabolism, leading to the generation of tricarboxylic acid (TCA) cycle intermediates. |
1(0,0,0,1) | Details |
| 19053364 | Schiavon M, Ertani A, Nardi S: Effects of an alfalfa protein hydrolysate on the gene expression and activity of enzymes of the tricarboxylic acid (TCA) cycle and nitrogen metabolism in Zea mays L. J Agric Food Chem. 2008 Dec 24;56(24):11800-8. The activity of a number of enzymes involved in carbon (C) metabolism (malate dehydrogenase, MDH; isocitrate dehydrogenase, IDH; citrate synthase, CS) and N reduction and assimilation reductase, NR; reductase, NiR; glutamine synthetase, GS; synthase, GOGAT; aspartate aminotransferase, AspAT) was significantly induced by EM supply to plants, and the transcription pattern of MDH, IDH, CS, and NR strongly correlated with data of enzyme activity. |
1(0,0,0,1) | Details |
| 17622976 | Celik I, Tuluce Y: Elevation protective role of Camellia sinensis and Urtica dioica infusion against trichloroacetic acid-exposed in rats. Phytother Res. 2007 Nov;21(11):1039-44. The preventive potential of the plant infusions was evaluated by measuring the level of serum marker enzymes, aspartate aminotransferase (AST), alanine aminotransferase (ALT), phosphokinase (CPK), acid phosphatase (ACP), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH); antioxidant defense systems, (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST) and catalase (CAT); and lipid peroxidation (malondialdehyde, MDA) content in various organs of rats. |
1(0,0,0,1) | Details |
| 17999340 | Celik I, Isik I: Determination of chemopreventive role of Foeniculum vulgare and Salvia officinalis infusion on trichloroacetic acid-induced increased serum marker enzymes lipid peroxidation and antioxidative defense systems in rats. Nat Prod Res. 2008 Jan 10;22(1):66-75. The chemopreventive potential of the plant infusions were evaluated by measuring levels of serum marker enzymes [aspartate aminotransferase (AST), alanin aminotransferase (ALT), phosphokinase (CPK), acid phosphatase (ACP), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH)], antioxidant defense systems (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST) and catalase (CAT)] and lipid peroxidation level (Malondialdehyde = MDA) in various tissues of rats. |
1(0,0,0,1) | Details |
| 16933615 | Xia MS, Hu CH, Zhao WY: [Study on the antibacterial mechanisms of -bearing montmorillonite] . Wei Sheng Wu Xue Bao. 2006 Jun 4;46(3):432-5. The activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and lactate dehydrogenase (LDH) of bacteria were examined and the results showed treatment with Cu-MMT could lead to significant release of intracellular enzymes from the tested bacteria suggesting that the permeability of the cell membrane increased and bacteria suffered injury. |
1(0,0,0,1) | Details |
| 19367038 | Xu X, Yang R, Wu N, Zhong P, Ke Y, Zhou L, Yuan J, Li G, Huang H, Wu B: Severe hypersensitivity dermatitis and liver dysfunction induced by occupational exposure to trichloroethylene. Ind Health. 2009 Apr;47(2):107-12. In addition, liver enlargement occurred in 3 patients, the abnormal rate of alanine aminotransferase (ALT), aspartate aminotransferase (AST), total (T-Bil) were 90.5%, 85.7% and 76.2%, respectively. 6 out of 15 patients were with abnormal electrocardiogram, and trichloroacetic acid (TCA) elevated in 14 patients (66.7%). |
1(0,0,0,1) | Details |
| 15927046 | Wang W, Hollmann R, Furch T, Nimtz M, Malten M, Jahn D, Deckwer WD: Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase. Proteome Sci. 2005 May 31;3:4. However, a short-term up-regulation of aspartate aminotransferase, an enzyme closely related to dextransucrase production, in the induced culture demonstrated the feasibility to use 2-DE method for monitoring dextransucrase production. |
1(0,0,0,1) | Details |
| 17436532 | Satyaparameshwar K, Reddy TR, Kumar NV: Effect of on protein metabolism of fresh water mussel, Lamellidens marginalis. J Environ Biol. 2006 May;27(2 Suppl):401-3. and Aspartate aminotransferase activities showed an increase, while GDH activity showed a decrease. |
1(0,0,0,1) | Details |
| 16416424 | Santos SS, Gibson GE, Cooper AJ, Denton TT, Thompson CM, Bunik VI, Alves PM, Sonnewald U: Inhibitors of the alpha-ketoglutarate dehydrogenase complex alter [1-13C] and [U-13C] glutamate metabolism in cerebellar granule neurons. J Neurosci Res. 2006 Feb 15;83(3):450-8. The findings are consistent with decreased KGDHC activity; increased alpha-ketoglutarate formation; increased transamination of alpha-ketoglutarate with and and new equilibrium position of the aspartate aminotransferase reaction. |
1(0,0,0,1) | Details |
| 18565563 | Ramdhan DH, Kamijima M, Yamada N, Ito Y, Yanagiba Y, Nakamura D, Okamura A, Ichihara G, Aoyama T, Gonzalez FJ, Nakajima T: Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1. Toxicol Appl Pharmacol. 2008 Sep 15;231(3):300-7. Epub 2008 May 2. The mice were exposed by inhalation to 0 (control), 1000, or 2000 ppm of TRI for 8 h a day, for 7 days, and TRI-hepatotoxicity was assessed by measuring plasma alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities and histopathology. |
1(0,0,0,1) | Details |