| Name | CFTR |
|---|---|
| Synonyms | ABC35; ABCC 7; ABCC7; ATP binding cassette transporter sub family C member 7; CF; CFTR; CFTR/MRP; MRP 7… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16390870 | Oberdorf J, Carlson EJ, Skach WR: Uncoupling proteasome peptidase and ATPase activities results in cytosolic release of an ER polytopic protein. J Cell Sci. 2006 Jan 15;119(Pt 2):303-13. Epub 2006 Jan 3. Here we examine the specific role of beta subunit function on polypeptide cleavage and membrane release of CFTR, a prototypical ER-associated degradation substrate with 12 transmembrane segments. |
4(0,0,0,4) | Details |
| 15917633 | Carlson E, Bays N, David L, Skach WR: Reticulocyte lysate as a model system to study endoplasmic reticulum membrane protein degradation. Methods Mol Biol. 2005;301:185-205. Here we describe techniques for preparing translation- and degradation-competent RRL, affinity depletion, identification of cytosolic factors involved in degrading the cystic fibrosis transmembrane conductance regulator (CFTR), and reconstitution of ERAD by add-back of purified recombinant proteins. |
1(0,0,0,1) | Details |