| Name | serotonin transporter |
|---|---|
| Synonyms | Sodium dependent serotonin transporter; OCD1; 5 hydroxytryptamine transporter; 5HT transporter; 5HTT; HTT; OCD 1; SERT… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19948720 | Sinning S, Musgaard M, Jensen M, Severinsen K, Celik L, Koldso H, Meyer T, Bols M, Jensen HH, Schiott B, Wiborg O: Binding and orientation of tricyclic antidepressants within the central substrate site of the human serotonin transporter. J Biol Chem. 2010 Mar 12;285(11):8363-74. Epub 2009 Nov 30. |
5(0,0,0,5) | Details |
| 17617292 | Smits KM, Smits LJ, Schouten JS, Peeters FP, Prins MH: Does pretreatment testing for serotonin transporter polymorphisms lead to earlier effects of drug treatment in patients with major depression? A decision-analytic model. Clin Ther. 2007 Apr;29(4):691-702. |
4(0,0,0,4) | Details |
| 17592096 | Diem SJ, Blackwell TL, Stone KL, Yaffe K, Haney EM, Bliziotes MM, Ensrud KE: Use of antidepressants and rates of hip bone loss in older women: the study of osteoporotic fractures. Arch Intern Med. 2007 Jun 25;167(12):1240-5. BACKGROUND: Serotonin transporters have recently been described in bone, raising the possibility that medications that block reuptake could affect bone metabolism. |
1(0,0,0,1) | Details |
| 17687333 | Singh SK, Yamashita A, Gouaux E: Antidepressant binding site in a bacterial homologue of neurotransmitter transporters. Nature. 2007 Aug 23;448(7156):952-6. Epub 2007 Aug 8. Antagonist dissociation experiments on the serotonin transporter (SERT) have also unveiled the existence of a low-affinity allosteric site that slows the dissociation of inhibitors from a separate high-affinity site. |
1(0,0,0,1) | Details |
| 20029939 | Ressler KJ, Bradley B, Mercer KB, Deveau TC, Smith AK, Gillespie CF, Nemeroff CB, Cubells JF, Binder EB: Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms. Am J Med Genet B Neuropsychiatr Genet. 2010 Apr 5;153B(3):812-24. |
1(0,0,0,1) | Details |
| 20060080 | Warden SJ, Hassett SM, Bond JL, Rydberg J, Grogg JD, Hilles EL, Bogenschutz ED, Smith HD, Fuchs RK, Bliziotes MM, Turner CH: Psychotropic drugs have contrasting skeletal effects that are independent of their effects on physical activity levels. Bone. 2010 Apr;46(4):985-92. Epub 2010 Jan 6. Pharmacological inhibition of the (5-HT) transporter (5-HTT) using a SSRI reduced in vivo gains in lower extremity BMD, and negatively altered ex vivo measures of femoral and spinal bone density, architecture and mechanical properties. |
1(0,0,0,1) | Details |