Protein Information

Name catalase
Synonyms CAT; Catalase; Erythrocyte derived growth promoting factor; Carnitine O acetyltransferase; Carnitine acetylase; Carnitine acetyltransferase; CAT; Catalases…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
15942004 Lefebre MD, Flannagan RS, Valvano MA: A minor catalase/peroxidase from Burkholderia cenocepacia is required for normal aconitase activity. Microbiology. 2005 Jun;151(Pt 6):1975-85.

3(0,0,0,3) Details
20131912 Seenarain V, Viola HM, Ravenscroft G, Casey TM, Lipscombe RJ, Ingley E, Laing NG, Bringans SD, Hool LC: Evidence of Altered Guinea Pig Ventricular Cardiomyocyte Protein Expression and Growth in Response to a 5 min in vitro Exposure to H (2) O (2). J Proteome Res. 2010 Feb 26.


Guinea pig ventricular myocytes were exposed to 30 muM H (2) O (2) for 5 min followed by 10 units/mL catalase to degrade the H (2) O (2), and effects on protein expression were examined 48 h later.
2(0,0,0,2) Details
19716523 Tajima S, Itoh Y, Sugimoto T, Kato T, Park EY: Increased riboflavin production from activated bleaching earth by a mutant strain of Ashbya gossypii. J Biosci Bioeng. 2009 Oct;108(4):325-9.


The specific intracellular catalase activity after 3 d of culture was 6-fold higher in the mutant than in the wild-type strain.
1(0,0,0,1) Details
17574827 Buddhan S, Sivakumar R, Dhandapani N, Ganesan B, Anandan R: Protective effect of dietary squalene supplementation on mitochondrial function in liver of aged rats. Prostaglandins Leukot Essent Fatty Acids. 2007 Jun;76(6):349-55. Epub 2007 Jun 15.


Supplementation with squalene also maintained the mitochondrial antioxidant defense system at higher rate by increasing the level of reduced glutathione and the activities of glutathione-dependent antioxidant enzymes (glutathione peroxidase and glutathione-S-transferase) and antiperoxidative enzymes (superoxide dismutase and catalase) in the liver of young and aged rats.
1(0,0,0,1) Details
16758861 Fedorov DV, Podkopaeva DA, Miroshnichenko ML, Bonch-Osmolovskaia EA, Lebedinskii AV, Grabovich MIu: [Investigation of the catabolism of acetate and peptides in the new anaerobic thermophilic bacterium Caldithrix abyssi]. Mikrobiologiia. 2006 Mar-Apr;75(2):154-9.


The activity of antioxidant enzymes (catalase and superoxide dismutase) was detected.
1(0,0,0,1) Details
12210539 Poon R, Nakai J, Yagminas A, Benoit F, Moir D, Chu I, Valli VE: Subchronic toxicity of chloral hydrate on rats: a drinking water study. J Appl Toxicol. 2002 Jul-Aug;22(4):227-36.


Statistically significant treatment-related effects were biochemical in nature, with the most pronounced being increased liver catalase activity in male rats starting at 2 ppm.
1(0,0,0,1) Details
20199583 Kamaraj S, Anandakumar P, Jagan S, Ramakrishnan G, Devaki T: Hesperidin attenuates mitochondrial dysfunction during benzo (a) pyrene-induced lung carcinogenesis in mice. Fundam Clin Pharmacol. 2010 Feb 22.


B (a) P (50 mg/kg body weight)-induced mitochondrial abnormalities was evident from alterations in mitochondrial lipid peroxides, antioxidant status (superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glutathione-S-transferase, reduced glutathione, vitamin E, and vitamin C), major tricarboxylic acid (TCA) cycle enzyme activities (isocitrate dehydrogenase, succinate dehydrogenase, malate dehydrogenase, alpha-ketoglutarate dehydrogenase), electron transport chain (ETC) complexes activities and ATP levels.
1(0,0,0,1) Details
17622976 Celik I, Tuluce Y: Elevation protective role of Camellia sinensis and Urtica dioica infusion against trichloroacetic acid-exposed in rats. Phytother Res. 2007 Nov;21(11):1039-44.


The preventive potential of the plant infusions was evaluated by measuring the level of serum marker enzymes, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine phosphokinase (CPK), acid phosphatase (ACP), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH); antioxidant defense systems, reduced glutathione (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST) and catalase (CAT); and lipid peroxidation (malondialdehyde, MDA) content in various organs of rats.
1(0,0,0,1) Details
19298531 Chen DD, Dong YG, Liu D, He JG: Epigallocatechin-3-gallate attenuates cardiac hypertrophy partly via MAPKs signals in hypertensive rats. Clin Exp Pharmacol Physiol. 2009 Mar 2.


The activities of total superoxide dismutase, catalase, and glutathione peroxidase were increased in TCA group, which were blunted by EGCG treatment.
1(0,0,0,1) Details
17999340 Celik I, Isik I: Determination of chemopreventive role of Foeniculum vulgare and Salvia officinalis infusion on trichloroacetic acid-induced increased serum marker enzymes lipid peroxidation and antioxidative defense systems in rats. Nat Prod Res. 2008 Jan 10;22(1):66-75.


The chemopreventive potential of the plant infusions were evaluated by measuring levels of serum marker enzymes [aspartate aminotransferase (AST), alanin aminotransferase (ALT), creatine phosphokinase (CPK), acid phosphatase (ACP), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH)], antioxidant defense systems [Reduced glutathione (GSH), glutathione reductase (GR), superoxide dismutase (SOD), glutathione-S-transferase (GST) and catalase (CAT)] and lipid peroxidation level (Malondialdehyde = MDA) in various tissues of rats.
1(0,0,0,1) Details