| Name | PARP |
|---|---|
| Synonyms | COL11A2; PARP; Collagen alpha 2(XI) chain; Collagen alpha 2(XI) chain precursor; Collagen type XI alpha 2; Collagen type XI alpha 2 isoform 1; DFNA13; DFNB53… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15377881 | Zeng J, Hirai K, Yang GY, Ying W, Swanson RA, Kelly M, Mayer M, James TL, Litt L: Using 31P NMR spectroscopy at 14.1 Tesla to investigate PARP-1 associated energy failure and metabolic rescue in cerebrocortical slices. J Bioenerg Biomembr. 2004 Aug;36(4):415-9. It appears possible to use brain slices to quantitatively study PARP-related, -associated energy failure, and rescue with TCA metabolites. |
31(0,1,1,1) | Details |
| 12125093 | Bacurau RF, O'Toole CE, Newsholme P, Costa Rosa LF: Sub-lethal concentrations of activated complement increase rat lymphocyte utilization and oxidation while lethal concentrations cause death by a mechanism involving ATP depletion. Cell Biochem Funct. 2002 Sep;20(3):183-90. Nevertheless, the extent of cell death could be significantly reduced by the addition of inhibitors of the nuclear enzyme poly (ADP- polymerase (PARP). |
2(0,0,0,2) | Details |
| 16736046 | Zeng J, Yang GY, Ying W, Kelly M, Hirai K, James TL, Swanson RA, Litt L: improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. J Cereb Blood Flow Metab. 2007 Feb;27(2):304-15. Epub 2006 May 24. superfusion of PARP-injured brain slices helps replenish NAD (+) while providing metabolic fuel. |
1(0,0,0,1) | Details |