Protein Information

Name cyclin D1
Synonyms B cell CLL/lymphoma 1; B cell leukemia 1; BCL 1; BCL 1 oncogene; BCL1; CCND 1; CCND1; Cyclin D1…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
18942709 Zhou X, Zhang Z, Yang X, Chen W, Zhang P: Inhibition of cyclin D1 expression by cyclin D1 shRNAs in human oral squamous cell carcinoma cells is associated with increased cisplatin chemosensitivity. Int J Cancer. 2009 Jan 15;124(2):483-9.

A tumor transplantation model was generated to examine the cisplatin sensitivity of Tca/cisplatin after in vivo cyclin D1 silencing.
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16978399 Zhang P, Zhang Z, Zhou X, Qiu W, Chen F, Chen W: Identification of genes associated with cisplatin resistance in human oral squamous cell carcinoma cell line. BMC Cancer. 2006 Sep 15;6:224.


METHODS: A cisplatin-resistant cell line, Tca/cisplatin, was established from a cisplatin-sensitive cell line, Tca8113, which was derived from moderately-differentiated tongue squamous cell carcinoma.
0(0,0,0,0) Details