| Name | caspase (protein family or complex) |
|---|---|
| Synonyms | caspase; caspases |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20300697 | Ruan M, Yan M, Yang WJ, Qu XZ, Zhou XJ, Chen WT, Zhang CP: [Role of NF-kappaB pathway in shikonin induced apoptosis in oral squamous cell carcinoma Tca-8113 cells.]. Shanghai Kou Qiang Yi Xue. 2010 Feb;19(1):66-71. CONCLUSIONS: Anti-tumor effects of shikonin in Tca-8113 cells act at least partially through the inactivation of NF-kappaB pathway and subsequent activation of protease caspase family. |
81(1,1,1,1) | Details |
| 18167055 | Min R, Tong J, Wenjun Y, Wenhu D, Xiaojian Z, Jiacai H, Jian Z, Wantao C, Chenping Z: Growth inhibition and induction of apoptosis in human oral squamous cell carcinoma Tca-8113 cell lines by Shikonin was partly through the inactivation of NF-kappaB pathway. Phytother Res. 2008 Mar;22(3):407-15. These results raise the possibility that the anti-tumor effects of Shikonin in Tca-8113 cells are at least partly through the inactivation of the NF-kappaB pathway and subsequent activation of protease caspase family. |
81(1,1,1,1) | Details |
| 16162973 | Knight LA, Conroy M, Fernando A, Polak M, Kurbacher CM, Cree IA: Pilot studies of the effect of zoledronic acid (Zometa) on tumor-derived cells ex vivo in the ATP-based tumor chemosensitivity assay. Anticancer Drugs. 2005 Oct;16(9):969-76. In the tumor-derived cells, zoledronic acid showed concentration-dependent inhibition with a median IC50 for all tumors tested of 17 muM and evidence of apoptosis (caspase activation). |
1(0,0,0,1) | Details |