Protein Information

Name glyceraldehyde 3 phosphate dehydrogenase
Synonyms CDABP0047; G3PD; GAPD; GAPD protein; GAPDH; Glyceraldehyde 3 phosphate dehydrogenase; GAPD proteins; Glyceraldehyde 3 phosphate dehydrogenases

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
20064709 Chen XC, Song H, Fang T, Cao JM, Ren HJ, Bai JX, Xiong J, Ouyang PK, Ying HJ: Enhanced cyclic adenosine monophosphate production by Arthrobacter A302 through rational redistribution of metabolic flux. Bioresour Technol. 2010 May;101(9):3159-63. Epub 2010 Jan 12.


Meanwhile, the specific activities of glyceraldehyde 3-phosphate dehydrogenase, phosphofructokinase and pyruvate kinase were decreased by 66%, 61%, and 46%, respectively.
1(0,0,0,1) Details
17054944 Paskulin R, Jamnik P, Zivin M, Raspor P, Strukelj B: Ibogaine affects brain energy metabolism. . Eur J Pharmacol. 2006 Dec 15;552(1-3):11-4. Epub 2006 Sep 16.


Enzymes of glycolysis and tricarboxylic acid (TCA) cycle namely glyceraldehyde-3-phosphate dehydrogenase, aldolase A, pyruvate kinase and malate dehydrogenase were induced.
1(0,0,0,1) Details
17258477 Kim Y, Nandakumar MP, Marten MR: Proteome map of Aspergillus nidulans during osmoadaptation. Fungal Genet Biol. 2007 Sep;44(9):886-95. Epub 2007 Jan 26.


Sequence homology and conserved domains were used to assign probable function to twenty-one proteins currently annotated as "hypothetical." In osmoadapted cells, there was an increased expression of glyceraldehyde-3-phosphate dehydrogenase and aldehyde dehydrogenase, as well as a decreased expression of enolase, suggesting an increased glycerol biosynthesis and decreased use of the TCA cycle.
1(0,0,0,1) Details
17927910 Lee SH, Park EW, Cho YM, Kim SK, Lee JH, Jeon JT, Lee CS, Im SK, Oh SJ, Thompson JM, Yoon D: Identification of differentially expressed genes related to intramuscular fat development in the early and late fattening stages of hanwoo steers. J Biochem Mol Biol. 2007 Sep 30;40(5):757-64.


BLAST searches revealed that expression of the MDH, PI4-K, ferritin, ICER, NID-2, WDNMI, telethonin, filamin, and desmin (DES) genes increased while that of GAPD, COP VII, ACTA1, CamK II, and nebulin decreased during the late fattening stage.
2(0,0,0,2) Details