| Name | receptor tyrosine kinases |
|---|---|
| Synonyms | C ret; Hydroxyaryl protein kinase; PTC; CDHF12; HSCR 1; HSCR1; MEN2A; MEN2B… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16317705 | Dent P, Fang Y, Gupta S, Studer E, Mitchell C, Spiegel S, Hylemon PB: Conjugated bile acids promote ERK1/2 and AKT activation via a pertussis toxin-sensitive mechanism in murine and human hepatocytes. Hepatology. 2005 Dec;42(6):1291-9. Several studies have argued that G-protein-coupled receptors (GPCR) have the capacity to promote activation of receptor tyrosine kinases. |
3(0,0,0,3) | Details |
| 18493886 | Martucciello G: Hirschsprung's disease, one of the most difficult diagnoses in pediatric surgery: a review of the problems from clinical practice to the bench. Eur J Pediatr Surg. 2008 Jun;18(3):140-9. In the interests of simplifying genetic molecular diagnosis, I suggest the following guidelines: 1) only in cases of total colonic aganglionosis (TCA) is it advisable to carry out full RET mutation screening (the mutation rate is up to 70 %); and 2) all HSCR patients should be tested only for standard MEN2A and MTC mutations. |
1(0,0,0,1) | Details |