Protein Information

Name CD8
Synonyms CD8; p32; MAL; CD8A; CD8a antigen; CD8a molecule; LEU2 T lymphocyte antigen; Leu2…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
17163140 Stolpnikova VN, Kochergina NI, Karpenko OM, Miroshnichenko IV: [Quantitative changes in characteristics of immunity in longlivers] . Zh Mikrobiol Epidemiol Immunobiol. 2006 Sep-Oct;(6):50-3.


In the presence of polymorbidity the low level of TSA was observed in 81% of examinees, with the quantitative deficiency in the relative and absolute number of CD3+CD8+ T-lymphocytes (62% and 78% respectively) and the excess in the number CD3+CD4-CD8- T-lymphocytes (42% and 57% respectively).
5(0,0,0,5) Details
16237081 Lopez MV, Adris SK, Bravo AI, Chernajovsky Y, Podhajcer OL: IL-12 and IL-10 expression synergize to induce the immune-mediated eradication of established colon and mammary tumors and lung metastasis. J Immunol. 2005 Nov 1;175(9):5885-94.


The antitumor effect of the combined immunotherapy was mainly dependent on CD8+ cells although CD4+ T cells also played a role.
1(0,0,0,1) Details