Protein Information

Name parathyroid hormone
Synonyms PTH; Parathormone; Parathyrin; Parathyroid hormone; Parathyroid hormone precursor; Parathormones; Parathyrins; Parathyroid hormones…

Compound Information

Name TCA
CAS 2,2,2-trichloroacetic acid

Reference List

PubMed Abstract RScore(About this table)
19779770 Kara M, Tellioglu G, Krand O, Fersahoglu T, Berber I, Erdogdu E, Ozel L, Titiz MI: Predictors of hypocalcemia occurring after a total/near total thyroidectomy. Surg Today. 2009;39(9):752-7. Epub 2009 Sep 24.

The perioperative serum total calcium (tCa, ionized calcium (iCa) and intact parathormone (iPTH) were measured perioperatively.
8(0,0,1,3) Details
15305508 Howard LL, Kass PH, Lamberski N, Wack RF: Serum concentrations of ionized calcium, vitamin D3, and parathyroid hormone in captive thick-billed parrots (Rhynchopsitta pachyrhyncha). J Zoo Wildl Med. 2004 Jun;35(2):147-53.

Serum collected from 68 thick-billed parrots (Rhynchopsitta pachyrhyncha) from 15 institutions was analyzed for ionized Ca (iCa), total Ca (tCa), P, total protein (TP), albumin (Alb), parathyroid hormone (PTH), and vitamin D3.
7(0,0,1,2) Details
14678292 Carnevale V, Manfredi G, Romagnoli E, De Geronimo S, Paglia F, Pepe J, Scillitani A, D'Erasmo E, Minisola S: Vitamin D status in female patients with primary hyperparathyroidism: does it play a role in skeletal damage?. Clin Endocrinol. 2004 Jan;60(1):81-6.

Serum total calcium (tCa), phosphate (P), creatinine (Cr) and total alkaline phosphatase activity (AP), together with 24-h (uCa 24 h) and spot fasting (uCa/Cr) urinary calcium, were measured by autoanalyser; ionized calcium (iCa) was assessed by an ion-specific electrode; intact parathyroid hormone (PTH) was measured by immunoradiometric assay (IRMA) and 25-hydroxyvitamin D (25-OHD) by radioimmunoassay (RIA).
7(0,0,1,2) Details
15822568 Toribio RE, Kohn CW, Hardy J, Rosol TJ: Alterations in serum parathyroid hormone and electrolyte concentrations and urinary excretion of electrolytes in horses with induced endotoxemia. J Vet Intern Med. 2005 Mar-Apr;19(2):223-31.

The goal of this study was to determine the effect of endotoxin (lipopolysaccharide [LPS]) administration to healthy horses on serum parathyroid hormone (PTH), ionized calcium (Ca2+) and total calcium (tCa), ionized magnesium (Mg2+) and total magnesium (tMg), phosphate (Pi), potassium (K+), sodium (Na+), chloride (Cl-), and insulin concentrations, and on the urinary excretion of these electrolytes.
7(0,0,1,2) Details
20124547 Avila M, Prado C, Ventura MD, Mora C, Briones D, Valdez H, Hurtado ME, Lindholm B, Qureshi A, Castillo-Henkel C, Paniagua R: Vitamin D receptor gene, biochemical bone markers and bone mineral density in Mexican women on dialysis. Nephrol Dial Transplant. 2010 Feb 2.

METHODS: In a cross-sectional study, 197 women (42 +/- 10 years; 25% with diabetes mellitus (DM); body mass index (BMI) 25.26 +/- 4.77 kg/m (2)) treated by PD (72%) or HD (28%) underwent measurements of BMD (measured at the calcaneus by quantitative ultrasound; expressed as T- and Z-scores) and plasma total calcium (tCa), intact parathyroid hormone 1-84 (iPTH), phosphorus, albumin, glucose, osteoprotegerin (OPG), fetuin-A, intact osteocalcin-49 and N-MID fragment 1-43 aa (N-MID osteocalcin) N-terminal propeptide of type 1 procollagen (PINP) and C-terminal telopeptide-beta aspartic acid (BCL).
6(0,0,1,1) Details
14507273 Bolan CD, Cecco SA, Yau YY, Wesley RA, Oblitas JM, Rehak NN, Leitman SF: Randomized placebo-controlled study of oral calcium carbonate supplementation in plateletpheresis: II. Transfusion. 2003 Oct;43(10):1414-22.

RESULTS: Oral Ca induced dose-sensitive changes in parathyroid hormone (iPTH), total (tCa), and ionized (iCa) calcium levels.
6(0,0,1,1) Details
16621369 Hu Z, Niu H, Yang X, Li H, Sang G, Li B: Recombinant human parathyroid hormone 1-34: pharmacokinetics, tissue distribution and excretion in rats. Int J Pharm. 2006 Jul 24;317(2):144-54. Epub 2006 Mar 12.

2(0,0,0,2) Details
18000836 Murao N, Ishigai M, Yasuno H, Shimonaka Y, Aso Y: Simple and sensitive quantification of bioactive peptides in biological matrices using liquid chromatography/selected reaction monitoring mass spectrometry coupled with trichloroacetic acid clean-up. Rapid Commun Mass Spectrom. 2007;21(24):4033-8.


This method was applied to determine the synthetic parathyroid hormone (PTH) analog (MW 1721) in rat plasma and human hepcidin-25 (MW 2789) in human serum.
1(0,0,0,1) Details
16881844 Lopez I, Estepa JC, Mendoza FJ, Rodriguez M, Aguilera-Tejero E: Serum concentrations of calcium, phosphorus, magnesium and calciotropic hormones in donkeys. Am J Vet Res. 2006 Aug;67(8):1333-6.

PROCEDURES: Total calcium (tCa), total magnesium (tMg), and inorganic phosphorus (P) concentrations were measured in serum samples via spectrophotometry.
Parathyroid hormone (PTH) and calcitriol (CTR) concentrations were measured via radioimmunoassay.
1(0,0,0,1) Details
17643363 Spasovski G, Gelev S, Masin-Spasovska J, Selim G, Sikole A, Vanholder R: Improvement of bone and mineral parameters related to adynamic bone disease by diminishing dialysate calcium. Bone. 2007 Oct;41(4):698-703. Epub 2007 Jun 29.


The groups did not differ in the mean tCa before dialysis, but this parameter was significantly higher in the HCD group vs.
0(0,0,0,0) Details