| Name | CCR8 |
|---|---|
| Synonyms | C C CKR 8; Chemokine receptor like 1; C C chemokine receptor type 8; CC CKR8; CC chemokine receptor 8; CC chemokine receptor CHEMR1; CC CKR 8; CCR 8… |
| Name | TCA |
|---|---|
| CAS | 2,2,2-trichloroacetic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17164723 | Xie JF, Wang G, Debonera F, Han R, Dorf ME, Hancock W, Olthoff KM: Selective neutralization of the chemokine TCA3 reduces the increased injury of partial versus whole liver transplants induced by cold preservation. Transplantation. 2006 Dec 15;82(11):1501-9. Quantitative analysis showed that compared with expression in whole grafts harvested after the same period of cold ischemia, partial grafts had eightfold more T-cell activation gene (TCA)-3 (CCL1) chemokine messenger RNA (mRNA) expression (P <0.01) and sixfold more inducible protein (IP)-10 chemokine (CCL10) mRNA expression (P <0.01), as well as increased expression of the chemokine receptors CCR8 (receptor for TCA3) and CXCR3 (receptor for IP-10; P <0.01). |
1(0,0,0,1) | Details |
| 12496446 | Chung CD, Kuo F, Kumer J, Motani AS, Lawrence CE, Henderson WR Jr, Venkataraman C: CCR8 is not essential for the development of inflammation in a mouse model of allergic airway disease. J Immunol. 2003 Jan 1;170(1):581-7. Th2 cells selectively express CCR3, CCR4, and CCR8, which could direct their trafficking to sites of allergic inflammation. |
3(0,0,0,3) | Details |
| 15494499 | Singh UP, Singh S, Ravichandran P, Taub DD, Lillard JW Jr: Viral macrophage-inflammatory protein-II: a viral chemokine that differentially affects adaptive mucosal immunity compared with its mammalian counterparts. J Immunol. 2004 Nov 1;173(9):5509-16. These CCR8 ligands significantly enhanced Ag-specific serum and mucosal Abs through increasing Th2 cytokine secretion by CD4+ T cells. |
2(0,0,0,2) | Details |
| 18940934 | Wiener Z, Pocza P, Racz M, Nagy G, Tolgyesi G, Molnar V, Jaeger J, Buzas E, Gorbe E, Papp Z, Rigo J, Falus A: IL-18 induces a marked gene expression profile change and increased Ccl1 (I-309) production in mouse mucosal mast cell homologs. Int Immunol. 2008 Dec;20(12):1565-73. Epub 2008 Oct 21. The Ccl1 receptor (CCR8) is known to be expressed by T (h) 2 cells and is involved in their recruitment. |
1(0,0,0,1) | Details |