Protein Information

Name IL 8
Synonyms 3 10C; AMCF I; CXC chemokine ligand 8; CXCL 8; CXCL8; Emoctakin; GCP 1; GCP1…

Compound Information

Name copper sulfate
CAS sulfuric acid copper(2+) salt (1:1)

Reference List

PubMed Abstract RScore(About this table)
12964812 Geisel J, Jodden V, Obeid R, Knapp JP, Bodis M, Herrmann W: Stimulatory effect of homocysteine on interleukin-8 expression in human endothelial cells. Clin Chem Lab Med. 2003 Aug;41(8):1045-8.

By co-incubation of endothelial cells with homocysteine and copper sulfate, a further elevation of interleukin-8 expression (251% of controls) was observed, whereas copper sulfate alone had no stimulatory effect.
7(0,0,0,7) Details
18021535 Wan XH, Li YW, Luo XP: [Curcumin attenuated the lipid peroxidation and apoptotic liver injury in copper-overloaded rats]. Zhonghua Er Ke Za Zhi. 2007 Aug;45(8):604-8.

The expressions of TNF-alpha mRNA and IL-8 mRNA were observed by RT-PCR.
Copper-overloaded rat model was established by feeding with forage containing 1 g/kg copper sulfate and water with 0.185% copper sulfate for 8 weeks or 12 weeks.
5(0,0,0,5) Details