| Name | acetylcholine receptors (protein family or complex) |
|---|---|
| Synonyms | Acetylcholine receptor; Acetylcholine receptors |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16805793 | Sugano T, Yanagita T, Yokoo H, Satoh S, Kobayashi H, Wada A: Enhancement of insulin-induced PI3K/Akt/GSK-3beta and ERK signaling by neuronal nicotinic receptor/PKC-alpha/ERK pathway: up-regulation of IRS-1/-2 mRNA and protein in chromaffin cells. J Neurochem. 2006 Jul;98(1):20-33. The increase in IRS-1/IRS-2 levels induced by was prevented by nicotinic acetylcholine receptor (nAChR) antagonists, the Ca (2+) chelator 1,2-bis (2-aminophenoxy)-ethane-N,N,N',N'-tetra- tetrakis-acetoxymethyl ester, cycloheximide or actinomycin D. |
31(0,1,1,1) | Details |
| 18784291 | Zhong C, Du C, Hancock M, Mertz M, Talmage DA, Role LW: Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by and for axonal targeting of alpha7 nicotinic acetylcholine receptors. J Neurosci. 2008 Sep 10;28(37):9111-6. |
2(0,0,0,2) | Details |
| 17614110 | Garcia-Rates S, Camarasa J, Escubedo E, Pubill D: Methamphetamine and 3,4-methylenedioxymethamphetamine interact with central nicotinic receptors and induce their up-regulation. Toxicol Appl Pharmacol. 2007 Sep 15;223(3):195-205. Epub 2007 May 26. Previous work from our group indicated that alpha7 nicotinic acetylcholine receptors (alpha7 nAChR) potentially play a role in methamphetamine (METH) and 3,4-methylenedioxymethamphetamine (MDMA) neurotoxicity. The heightened binding was inhibited by pretreatment with cycloheximide, suggesting the participation of newly synthesised proteins while inhibition of protein trafficking to plasma membrane did not block up-regulation. |
1(0,0,0,1) | Details |