| Name | protein is |
|---|---|
| Synonyms | ANX 2; p36; LIP 2; LIP2; ANX2; ANX2L4; ANX2P1; ANX2P2… |
| Name | cycloheximide |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15791453 | Murakami J, Asaumi J, Kawai N, Tsujigiwa H, Yanagi Y, Nagatsuka H, Inoue T, Kokeguchi S, Kawasaki S, Kuroda M, Tanaka N, Matsubara N, Kishi K: Effects of histone deacetylase inhibitor FR901228 on the expression level of telomerase reverse transcriptase in oral cancer. Cancer Chemother Pharmacol. 2005 Jul;56(1):22-8. Epub 2005 Mar 25. Moreover, cotreatment of protein synthesis inhibitor cycloheximide (CHX) resulted in the induction of hTERT transcription by FR901228. |
0(0,0,0,0) | Details |
| 16820941 | Otomo Y, Yamaguchi M: Regulatory effect of exogenous regucalcin on cell function in osteoblastic MC3T3-E1 cells: involvement of intracellular signaling factor. Int J Mol Med. 2006 Aug;18(2):321-7. This study supports the view that exogenous regucalcin regulates the function of osteoblastic cells, and that the effect of protein is mediated through signaling factors. The presence of regucalcin did not have a significant effect on protein and DNA contents in the cells cultured with cycloheximide (10 (-7) M), an inhibitor of protein synthesis, or 5,6-dichloro -1-beta-D-ribofuranosylbenzimidazole (10 (-6) M), an inhibitor of transcription activity; which each inhibitor caused a significant decrease in those contents. |
1(0,0,0,1) | Details |
| 17711404 | Chan SC, Lin SC, Li P: Regulation of Cidea protein stability by the ubiquitin-mediated proteasomal degradation pathway. Biochem J. 2007 Dec 1;408(2):259-66. However, little is known as to how the Cidea protein is regulated. In the present study we show that Cidea is a short-lived protein as measured by cycloheximide-based protein chase experiments in different cell lines or in differentiated brown adipocytes. |
1(0,0,0,1) | Details |
| 20067810 | Heller SR, Rodrigues Goulart H, Arthuso FS, Oliveira TL, Bartolini P, Soares CR: Synthesis, purification and characterization of recombinant glycosylated human prolactin (G-hPRL) secreted by cycloheximide-treated CHO cells. J Biotechnol. 2010 Feb 15;145(4):334-40. Epub 2010 Jan 11. This protein contains only one potential -linked glycosylation site, which is partially (10-30%) occupied when the protein is synthesized in eukaryotic cells. |
1(0,0,0,1) | Details |
| 16339571 | Han B, Mura M, Andrade CF, Okutani D, Lodyga M, dos Santos CC, Keshavjee S, Matthay M, Liu M: TNFalpha-induced long pentraxin PTX3 expression in human lung epithelial cells via JNK. J Immunol. 2005 Dec 15;175(12):8303-11. Long pentraxin 3 (PTX3), an acute-phase protein, is a newly clarified mediator for innate immunity and inflammation. Pretreatment with either actinomycin D or cycloheximide abolished TNF-alpha-induced PTX3 expression, indicating the requirement for both transcriptional and translational regulation. |
1(0,0,0,1) | Details |
| 16595698 | Woltje M, Tschoke B, von Bulow V, Westenfeld R, Denecke B, Graber S, Jahnen-Dechent W: CCAAT enhancer binding protein beta and hepatocyte nuclear factor 3beta are necessary and sufficient to mediate dexamethasone-induced up-regulation of alpha2HS-glycoprotein/fetuin-A gene expression. J Mol Endocrinol. 2006 Apr;36(2):261-77. Enhancement of Ahsg expression as a protective serum protein is desirable in several diseases including tissue remodelling after trauma and infection, kidney and heart failure, and cancer. |
1(0,0,0,1) | Details |
| 18957409 | Webb KJ, Laganowsky A, Whitelegge JP, Clarke SG: Identification of two SET domain proteins required for methylation of residues in yeast ribosomal protein Rpl42ab. J Biol Chem. 2008 Dec 19;283(51):35561-8. Epub 2008 Oct 28. We found that the yeast Rpl12ab protein is dimethylated at the N-terminal residue, trimethylated at -3 by Rkm2, and monomethylated at Arg-66. A slow growth phenotype was seen for the SET7 deletion strain and the double knock-out when grown in low concentrations of the eukaryotic protein synthesis inhibitor, cycloheximide. |
1(0,0,0,1) | Details |
| 18321792 | Paronetto MP, Bianchi E, Geremia R, Sette C: Dynamic expression of the RNA-binding protein Sam68 during mouse pre-implantation development. Gene Expr Patterns. 2008 May;8(5):311-22. Epub 2008 Feb 2. Sam68 protein is expressed throughout oocyte meiotic maturation and early embryogenesis. However, we found that inhibition of mRNA translation by either cycloheximide or puromycin in one-cell embryos caused the accumulation of Sam68 in cytoplasmic granules. |
1(0,0,0,1) | Details |
| 16098139 | Masuyama S, Tateishi S, Yomogida K, Nishimune Y, Suzuki K, Sakuraba Y, Inoue H, Ogawa M, Yamaizumi M: Regulated expression and dynamic changes in subnuclear localization of mammalian Rad18 under normal and genotoxic conditions. Genes Cells. 2005 Aug;10(8):753-62. These results suggest that in higher eukaryotes, the maintenance and dynamic translocation of Rad18 protein is important for postreplication repair. |
1(0,0,0,1) | Details |
| 17400707 | Qiu QS, Hardin SC, Mace J, Brutnell TP, Huber SC: Light and metabolic signals control the selective degradation of synthase in maize leaves during deetiolation. Plant Physiol. 2007 May;144(1):468-78. Epub 2007 Mar 30. The content and activity of Suc (Suc) synthase (SUS) protein is high in sink organs but low in source organs. However, SUS degradation was strongly inhibited by feeding cycloheximide or amino acids to detached leaves, while Suc feeding had no effect. |
1(0,0,0,1) | Details |
| 18066586 | Lee MO, Cho K, Kim SH, Jeong SH, Kim JA, Jung YH, Shim J, Shibato J, Rakwal R, Tamogami S, Kubo A, Agrawal GK, Jwa NS: Novel rice OsSIPK is a multiple stress responsive MAPK family member showing rhythmic expression at mRNA level. Planta. 2008 Apr;227(5):981-90. Epub 2007 Dec 8. A time course (30-120 min) experiment using a variety of elicitors and stresses revealed that the OsSIPK mRNA is strongly induced by jasmonic acid (JA), (SA), ethephon, abscisic acid, cycloheximide (CHX), JA/SA + CHX, cantharidin, okadaic acid, peroxide, and cold stress (12 degrees C), but not with wounding by cut, gaseous pollutants ozone, and dioxide, high temperature, ultraviolet C irradiation, and drought. Finally, we showed that the OsSIPK protein is localized to the nucleus. |
1(0,0,0,1) | Details |
| 18812520 | Remington M, Chtchetinin J, Ancheta K, Nghiemphu PL, Cloughesy T, Lai A: The L84F polymorphic variant of human O6-methylguanine-DNA methyltransferase alters stability in U87MG glioma cells but not temozolomide sensitivity. Neuro Oncol. 2009 Feb;11(1):22-32. Epub 2008 Sep 23. We confirmed that the wild-type (WT) eGFP-MGMT protein is properly localized within the nucleus and found that L84F, I143V/K178R, and L84F/I143V/K178R eGFP-MGMT variants exhibited nuclear localization patterns indistinguishable from WT. |
1(0,0,0,1) | Details |
| 16957816 | Kahle M, Pridalova J, Spacek M, Dzijak R, Hozak P: Nuclear myosin is ubiquitously expressed and evolutionary conserved in vertebrates. Histochem Cell Biol. 2007 Feb;127(2):139-48. Epub 2006 Sep 7. The lifespan of NMI is longer than 16 h as determined by cycloheximide translation block. A homologous protein is expressed in human, chicken, Xenopus, and zebrafish as shown by RACE analysis. |
1(0,0,0,1) | Details |
| 17848638 | Kershaw EE, Schupp M, Guan HP, Gardner NP, Lazar MA, Flier JS: PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo. Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1736-45. Epub 2007 Sep 11. -mediated induction of ATGL mRNA is rapid and is not inhibited by the protein synthesis inhibitor cycloheximide, indicating that intervening protein synthesis is not required for this effect. -mediated induction of ATGL mRNA and protein is inhibited by the PPARgamma-specific antagonist GW-9662 and is also significantly reduced following siRNA-mediated knockdown of PPARgamma, supporting the direct transcriptional regulation of ATGL by PPARgamma. |
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| 19506251 | Tang CT, Li S, Long C, Cha J, Huang G, Li L, Chen S, Liu Y: Setting the pace of the Neurospora circadian clock by multiple independent FRQ phosphorylation events. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10722-7. Epub 2009 Jun 8. Like PERIOD in animals, the Neurospora core circadian protein FRQ is progressively phosphorylated and becomes extensively phosphorylated before its degradation. |
1(0,0,0,1) | Details |
| 17603220 | Fujimoto N, Inoue K, Ohgusu Y, Hayashi Y, Yuasa H: Enhanced uptake of by treatment in HCT-15 human colon cancer cell line. Drug Metab Pharmacokinet. 2007 Jun;22(3):195-8. The effect of was almost completely suppressed when actinomycin D, an inhibitor of gene transcription, and cycloheximide, an inhibitor of protein synthesis, were added to the medium during the treatment. These results support the suggestion that a specific carrier protein is involved in uptake by HCT-15 cells and the carrier protein is one of those inducible by -induced cell differentiation. |
1(0,0,0,1) | Details |
| 17112665 | Kirkland RA, Franklin JL: Rate of neurite outgrowth in sympathetic neurons is highly resistant to suppression of protein synthesis: role of protein degradation/synthesis coupling. Neurosci Lett. 2007 Jan 3;411(1):52-5. Epub 2006 Nov 16. Because accumulation of protein is necessary for outgrowth to proceed normally, a perturbation in protein synthesis could cause a net change in the rate of accumulation of proteins with the result that neurite outgrowth rate increases or decreases. |
1(0,0,0,1) | Details |
| 15928597 | Pajak B, Orzechowski A: [FLIP--an enemy which might lose the battle against the specific inhibitors of translation]. Postepy Hig Med Dosw. 2005;59:140-9. In in vitro studies, such activity is exerted by cycloheximide or bisindolylmaleimide, either of which, at a low, non-toxic concentration, totally abrogates FLIP protein expression or, in turn, sensitizes cancer cells to death ligands. The assumed reduced viability/elevated mortality of cancer cells, including the most malicious (e.g. melanomas), upon treatment with specific metabolic inhibitors of FLIP makes feasible the search for synthetic or natural factors that may promise more efficacious treatment of deadly diseases where basal FLIP protein is overexpressed. |
1(0,0,0,1) | Details |
| 17595158 | Chen YF, Shakeel SN, Bowers J, Zhao XC, Etheridge N, Schaller GE: Ligand-induced degradation of the ethylene receptor ETR2 through a proteasome-dependent pathway in Arabidopsis. J Biol Chem. 2007 Aug 24;282(34):24752-8. Epub 2007 Jun 25. The ETR2 protein is initially induced by ethylene treatment, consistent with an increase in transcript levels. The ethylene-induced decrease in ETR2 levels is not affected by cycloheximide, an inhibitor of protein biosynthesis, but is affected by proteasome inhibitors, indicating a role for the proteasome in ETR2 degradation. |
1(0,0,0,1) | Details |
| 16475832 | Shukla S, Rai V, Banerjee D, Prasad R: Characterization of Cdr1p, a major multidrug efflux protein of Candida albicans: purified protein is amenable to intrinsic fluorescence analysis. Biochemistry. 2006 Feb 21;45(7):2425-35. |
1(0,0,0,1) | Details |
| 19211738 | Gagnon D, Joubert S, Senechal H, Fradet-Turcotte A, Torre S, Archambault J: Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4. J Virol. 2009 May;83(9):4127-39. Epub 2009 Feb 11. The steady-state levels of Rluc-E2 were quantified by measuring the amounts of associated luciferase activity, and its degradation was measured by monitoring the decrease in enzymatic activity occurring after a block of translation with cycloheximide. |
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| 19016568 | Malone JL, Nelson AC, Lieberman R, Anderson S, Holt JT: Oestrogen-mediated phosphorylation and stabilization of BRCA2 protein in breast. J Pathol. 2009 Feb;217(3):380-8. We have demonstrated that BRCA2 protein is specifically expressed in ER (+) breast cancers and are investigating a pathway that may show a link between E2 action and BRCA2 protein function in breast cancer. This increase seen in BRCA2 total and phospho-S3291 protein levels was found to be unaffected with cycloheximide pre-treatment, but decreased following tamoxifen, ICI 182,780 or roscovitine treatment. |
1(0,0,0,1) | Details |
| 18706457 | Shifley ET, Cole SE: Lunatic fringe protein processing by proprotein convertases may contribute to the short protein half-life in the segmentation clock. Biochim Biophys Acta. 2008 Dec;1783(12):2384-90. Epub 2008 Jul 25. LFNG protein is cleaved and released into the extracellular space, and here we examine the hypothesis that this secretion contributes to a short LFNG intracellular half-life, facilitating rapid oscillations within the segmentation clock. |
1(0,0,0,1) | Details |
| 15664650 | Walker R Jr, Saha L, Hill GC, Chaudhuri M: The effect of over-expression of the alternative oxidase in the procyclic forms of Trypanosoma brucei. Mol Biochem Parasitol. 2005 Feb;139(2):153-62. This suggests that the expression of two terminal oxidases and the coat protein is linked in T. brucei. |
1(0,0,0,1) | Details |
| 17535899 | Fu NY, Sukumaran SK, Yu VC: Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10051-6. Epub 2007 May 29. Here, we report that MOAP-1 protein is rapidly up-regulated by multiple apoptotic stimuli in mammalian cells. Mitochondria depleted of short-lived proteins by cycloheximide (CHX) become resistant to Bax-mediated cytochrome c release. |
1(0,0,0,1) | Details |
| 17596701 | Rebelo S, Vieira SI, Esselmann H, Wiltfang J, da Cruz e Silva EF, da Cruz e Silva OA: 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits a decreased turnover rate. Neurodegener Dis. 2007;4(2-3):78-87. |
1(0,0,0,1) | Details |
| 19018993 | Ham JH, Majerczak D, Ewert S, Sreerekha MV, Mackey D, Coplin D: WtsE, an AvrE-family type III effector protein of Pantoea stewartii subsp. stewartii, causes cell death in non-host plants. Mol Plant Pathol. 2008 Sep;9(5):633-43. WtsE, a type III secreted effector protein, is essential for the virulence of Pnss on corn. WtsE-induced cell death in N. benthamiana, tobacco and beet resembled a hypersensitive response and in N. benthamiana it was delayed by cycloheximide. |
1(0,0,0,1) | Details |
| 16518688 | Chen Y, Yee D, Magnuson T: A novel mouse Smad4 mutation reduces protein stability and wild-type protein levels. Mamm Genome. 2006 Mar;17(3):211-9. Epub 2006 Mar 3. Biochemical characterization indicated that the truncated protein is able to form a complex with the wild-type protein, thus targeting it for proteasomal degradation as well. |
1(0,0,0,1) | Details |
| 15831954 | Nal B, Chan C, Kien F, Siu L, Tse J, Chu K, Kam J, Staropoli I, Crescenzo-Chaigne B, Escriou N, van der Werf S, Yuen KY, Altmeyer R: Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E. J Gen Virol. 2005 May;86(Pt 5):1423-34. Pulse-chase labelling and confocal microscopy in the presence of protein translation inhibitor cycloheximide revealed that the E protein has a short half-life of 30 min. E protein is found in bright perinuclear patches colocalizing with endoplasmic reticulum markers. |
1(0,0,0,1) | Details |
| 16176349 | Elliott E, Atlas R, Lange A, Ginzburg I: Brain-derived neurotrophic factor induces a rapid dephosphorylation of tau protein through a PI-3 Kinase signalling mechanism. Eur J Neurosci. 2005 Sep;22(5):1081-9. Hyperphosphorylation and intracellular fibrillar formation of tau protein is a pathology found in Alzheimer's disease (AD) brains, and in a variety of neurodegenerative disorders referred to as 'taupathies'. |
1(0,0,0,1) | Details |
| 15650164 | Cheng G, Feng Z, He B: Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma (1) 34.5 protein. J Virol. 2005 Feb;79(3):1379-88. Together, these observations suggest that regulation of eIF-2alpha phosphorylation by the gamma (1) 34.5 protein is an efficient way to antagonize the inhibitory activity of PKR as well as PERK during productive infection. The virus-induced phosphorylation of PERK is blocked by cycloheximide but not by suggesting that the accumulation of viral proteins in the ER is essential. |
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| 15735697 | Chen C, Sun X, Ran Q, Wilkinson KD, Murphy TJ, Simons JW, Dong JT: Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells. Oncogene. 2005 May 5;24(20):3319-27. These results suggest that KLF5 protein is degraded at least in part through ubiquitination-proteasome pathway, which may have become hyperactive for KLF5 in cancer cells. |
1(0,0,0,1) | Details |
| 19137541 | Rizzi F, Caccamo AE, Belloni L, Bettuzzi S: Clusterin is a short half-life, poly-ubiquitinated protein, which controls the fate of prostate cancer cells. J Cell Physiol. 2009 May;219(2):314-23. Inhibition of protein synthesis by cycloheximide showed that CLU half-life is less than 2 h. Quite surprisingly, we also found that the turnover of CLU protein is very rapid and tightly regulated by ubiquitin-proteasome mediated degradation. |
1(0,0,0,1) | Details |
| 15685448 | Tahara E Jr, Tahara H, Kanno M, Naka K, Takeda Y, Matsuzaki T, Yamazaki R, Ishihara H, Yasui W, Barrett JC, Ide T, Tahara E: G1P3, an interferon inducible gene 6-16, is expressed in gastric cancers and inhibits mitochondrial-mediated apoptosis in gastric cancer cell line TMK-1 cell. Cancer Immunol Immunother. 2005 Aug;54(8):729-40. Epub 2005 Feb 1. However, the function of 6-16 protein is unknown. One of exceptional gastric cancer cell line, TMK-1, which do not express detectable 6-16, is sensitive to apoptosis induced by cycloheximide (CHX), 5-fluorouracil (5-FU) and serum-deprivation. |
1(0,0,0,1) | Details |
| 16036110 | Zhang L, Zhu H, Teraishi F, Davis JJ, Guo W, Fan Z, Fang B: Accelerated degradation of caspase-8 protein correlates with TRAIL resistance in a DLD1 human colon cancer cell line. Neoplasia. 2005 Jun;7(6):594-602. Thus, accelerated degradation of caspase-8 protein is one of the mechanisms that lead to TRAIL resistance. |
1(0,0,0,1) | Details |
| 20096397 | Bolduc V, Marlow G, Boycott KM, Saleki K, Inoue H, Kroon J, Itakura M, Robitaille Y, Parent L, Baas F, Mizuta K, Kamata N, Richard I, Linssen WH, Mahjneh I, de Visser M, Bashir R, Brais B: Recessive mutations in the putative -activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies. Am J Hum Genet. 2010 Feb 12;86(2):213-21. Epub 2010 Jan 21. Though the function of the ANO5 protein is still unknown, its putative -activated chloride channel function may lead to important insights into the role of deficient skeletal muscle membrane repair in muscular dystrophies. |
1(0,0,0,1) | Details |
| 16637064 | Choi W, Proctor L, Xia Q, Feng Y, Gerner EW, Chiao PJ, Hamilton SR, Zhang W: Inactivation of IkappaB contributes to transcriptional activation of / N (1)-acetyltransferase. Mol Carcinog. 2006 Sep;45(9):685-93. ActD alone blocked the induction of SSAT expression; however, the combination of CHX and DENSPM markedly induced SSAT expression and caused mitochondrial damage, suggesting that an inhibitory labile protein is involved in SSAT transactivation. |
1(0,0,0,1) | Details |
| 18590050 | Cavanaugh AH, Evans A, Rothblum LI: Mammalian Rrn3 is required for the formation of a transcription competent preinitiation complex containing RNA polymerase I. Gene Expr. 2008;14(3):131-47. Mammalian Rrn3, an essential, polymerase-associated protein, is inactivated when cells are treated with cycloheximide, resulting in the inhibition of transcription by RNA polymerase I. |
31(0,1,1,1) | Details |
| 18194670 | Gressner OA, Lahme B, Gressner AM: Gc-globulin (vitamin D binding protein) is synthesized and secreted by hepatocytes and internalized by hepatic stellate cells through Ca (2+)-dependent interaction with the megalin/gp330 receptor. Clin Chim Acta. 2008 Apr;390(1-2):28-37. Epub 2007 Dec 23. Cytoskeletal stainings of gc-globulin and alpha-smooth-muscle actin in hepatic stellate cells and the identification of the receptors megalin/gp330, HCAM/CD44, cubilin and annexin A2 were performed with confocal immunocytochemistry, immunoblotting and/or FACS-analysis. RESULTS: Hepatocytes synthesize and secrete gc-globulin as shown by RT-PCR and [(35) S]- labelling, which could be suppressed by cycloheximide. |
2(0,0,0,2) | Details |
| 16234850 | Abu-Farha M, Niles J, Willmore WG: Erythroid-specific synthase protein is stabilized by low and proteasomal inhibition. Biochem Cell Biol. 2005 Oct;83(5):620-30. We examined protein turnover of ALAS2 in the presence of cycloheximide in K562 cells. |
1(0,0,0,1) | Details |
| 16331262 | Li N, Li H, Cherukuri P, Farzan S, Harmes DC, DiRenzo J: TA-p63-gamma regulates expression of DeltaN-p63 in a manner that is sensitive to p53. Oncogene. 2006 Apr 13;25(16):2349-59. We further show that in cells in which p53 is expressed TA-p63-gamma protein is destabilized in a manner that is p53 dependent and sensitive to pharmacologic inhibition of the 26S proteosome. |
1(0,0,0,1) | Details |
| 15574423 | Yamada A, Irie K, Hirota T, Ooshio T, Fukuhara A, Takai Y: Involvement of the annexin II-S100A10 complex in the formation of E-cadherin-based adherens junctions in Madin-Darby canine kidney cells. J Biol Chem. 2005 Feb 18;280(7):6016-27. Epub 2004 Dec 1. We found here that this recruitment was dependent on protein synthesis, because a protein synthesis inhibitor, cycloheximide, prevented the accumulation of E-cadherin. |
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| 16572728 | Balakrishnan K, De Maio A: Heat shock protein 70 binds its own messenger ribonucleic acid as part of a gene expression self-limiting mechanism. Cell Stress Chaperones. 2006 Spring;11(1):44-50. HSP70, the major stress-induced heat shock protein, is involved in repair and protection after the insult. |
2(0,0,0,2) | Details |
| 18381294 | Lin MT, Kuo IH, Chang CC, Chu CY, Chen HY, Lin BR, Sureshbabu M, Shih HJ, Kuo ML: Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion. J Biol Chem. 2008 Jun 6;283(23):15807-15. Epub 2008 Apr 1. Using cycloheximide and MG132, we demonstrated that the Cyr61-mediated HIF-1alpha up-regulation was through de novo protein synthesis, rather than increased protein stability. rCyr61 could also activate the PI3K/AKT/mTOR and ERK1/2 signaling pathways, both of which were essential for HIF-1alpha protein accumulation. |
0(0,0,0,0) | Details |
| 17374524 | Gao Y, Pagnon J, Feng HC, Konstantopolous N, Jowett JB, Walder K, Collier GR: Secretion of the -regulated selenoprotein SEPS1 from hepatoma cells. Biochem Biophys Res Commun. 2007 May 11;356(3):636-41. Epub 2007 Mar 12. The secretion can be abolished by the ER-Golgi transport inhibitor Brefeldin A and by the protein synthesis inhibitor cycloheximide. |
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