Protein Information

Name lactate dehydrogenase (protein family or complex)
Synonyms LDH; lactate dehydrogenase; lactate dehydrogenases

Compound Information

Name oxytetracycline
CAS

Reference List

PubMed Abstract RScore(About this table)
8037569 Krakhmaleva IN, Vlasov VI, Telesnina GN, Krasnova TP, Vladimirov AV, Sazykin IuO: [Dynamics of the content of glycolysis enzymes in Streptomyces rimosus as it relates to the problem of regulation of oxytetracycline biosynthesis]. Antibiot Khimioter. 1993 Aug-Sep;38(8-9):11-5.

The activities of the key glycolytic enzymes i.e. hexokinase, phosphofructokinase, pyruvate kinase and lactate dehydrogenase were detected and investigated in 3 strains of Streptomyces rimosus differing in the level of the oxytetracycline production.
31(0,1,1,1) Details
16635103 Pari L, Gnanasoundari M: Influence of naringenin on oxytetracycline mediated oxidative damage in rat liver. Basic Clin Pharmacol Toxicol. 2006 May;98(5):456-61.

Intraperitonial administration of oxytetracycline 200 mg/kg for 15 days resulted a significant elevation in serum hepatospecific markers such as aspartate transaminase, alanine transaminase, alkaline phosphatase, lactate dehydrogenase, and bilirubin and the levels of lipid peroxidation markers (thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxides) in liver.
12(0,0,2,2) Details
11549049 Rule R, Moreno L, Serrano JM, Roman AG, Moyano R, Garcia J: Pharmacokinetics and residues in milk of oxytetracyclines administered parenterally to dairy goats. Aust Vet J. 2001 Jul;79(7):492-6.

OBJECTIVE: To determine for two commercial preparations of oxytetracycline (OTC) the pharmacokinetic behaviour, the presence of detectable milk residues and the penetration in milk of OTC administered by intravenous (IV) (conventional formulation [CF]) and intramuscular (IM) routes (CF and long-acting [LA] formulations) in goats producing milk.
The effects of these formulations on plasma activity values of creatine kinase (CK) and lactate dehydrogenase (LDH) were also determined as indicators of tissue damage.
1(0,0,0,1) Details
8410603 Nip LH, Uitto VJ, Golub LM: Inhibition of epithelial cell matrix metalloproteinases by tetracyclines. J Periodontal Res. 1993 Sep;28(5):379-85.


The effects of tetracyclines on periodontal epithelial cells were investigated by culturing cells from porcine rests of Malassez in the presence of oxytetracycline, doxycycline or one of two analogues of tetracycline bearing no antimicrobial activity.
0(0,0,0,0) Details