Name | superoxide dismutase |
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Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
Name | oxytetracycline |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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16635103 | Pari L, Gnanasoundari M: Influence of oxytetracycline mediated oxidative damage in rat liver. Basic Clin Pharmacol Toxicol. 2006 May;98(5):456-61. Oxytetracycline also caused a significant reduction in the activities of superoxide dismutase, catalase, peroxidase, (GSH), and in liver. |
on 87(1,1,2,2) | Details |
10613865 | Avery SV, Malkapuram S, Mateus C, Babb KS: Superoxide dismutase is required for oxytetracycline resistance of Saccharomyces cerevisiae. J Bacteriol. 2000 Jan;182(1):76-80. |
/zinc-6(0,0,1,1) | Details |
17050244 | Gnanasoundari M, Pari L: Impact of oxytetracycline-mediated oxidative damage in kidney of rats. Ren Fail. 2006;28(7):599-605. A significant increase in lipid peroxidation markers (TBARS and lipid hydroperoxide) and decrease in antioxidant enzymes (superoxide dismutase, catalase, and peroxidase) and low molecular weight antioxidants and levels were also observed in oxytetracycline-treated rats. |
on 6(0,0,1,1) | Details |
12897486 | Topsakal C, Kilic N, Ozveren F, Akdemir I, Kaplan M, Tiftikci M, Gursu F: Effects of oxytetracycline on lipid peroxidation, antioxidant defense system, paraoxonase (PON1) activities, and levels in an animal model of spinal cord injury. Spine (Phila Pa 1976). 2003 Aug 1;28(15):1643-52. Spinal cord tissue and blood malonyldialdehyde and plasma levels, plasma glutathione peroxidase, superoxide dismutase, paraoxonase activities were assayed. |
and 3(0,0,0,3) | Details |
3034858 | Martin JP Jr, Colina K, Logsdon N: Role of phototoxicity of tetracyclines toward Escherichia coli B. J Bacteriol. 1987 Jun;169(6):2516-22. The rate of reduction was dependent on the tetracycline concentration and on the derivative being examined, with doxycycline greater than or equal to demeclocycline greater than tetracycline greater than oxytetracycline. Tetracycline-mediated cytochrome c reduction was dependent and inhibited up to 70% by superoxide dismutase. |
radicals in the 3(0,0,0,3) | Details |
11557497 | Angrave FE, Avery SV: Antioxidant functions required for insusceptibility of Saccharomyces cerevisiae to tetracycline antibiotics. Antimicrob Agents Chemother. 2001 Oct;45(10):2939-42. Cu,Zn superoxide dismutase (Sod1) is required for insusceptibility of Saccharomyces cerevisiae to oxytetracycline (OTC). |
2(0,0,0,2) | Details |
3039994 | Li AS, Roethling HP, Cummings KB, Chignell CF: O2- photogenerated from aqueous solutions of tetracycline antibiotics (pH 7.3) as evidenced by DMPO spin trapping and cytochrome c reduction. Biochem Biophys Res Commun. 1987 Aug 14;146(3):1191-5. UV-irradiation of several tetracycline antibiotics in aqueous buffer (pH 7.3) resulted in the generation of the radical (O2-) which was detected by cytochrome c reduction and by spin trapping with 5,5-dimethyl-1-pyrroline-N-oxide and was inhibited by superoxide dismutase. A comparison of the O2- yields from the tetracyclines examined showed the trend chlortetracycline (CTC) greater than oxytetracycline (OXY) greater than demeclocycline (DEM) much greater than (doxycycline (DOXY) = tetracycline (TC) = minocycline (MINO) = 0). |
1(0,0,0,1) | Details |
15105154 | Avery AM, Goddard HJ, Sumner ER, Avery SV: blocks the accumulation and activity of tetracyclines in bacteria. Antimicrob Agents Chemother. 2004 May;48(5):1892-4. The effect of Fe was independent of superoxide dismutase activity and of intracellular Fe, but accumulation of tetracyclines was blocked in high-Fe medium. |
1(0,0,0,1) | Details |
14647012 | Sapmaz E, Ayar A, Celik H, Sapmaz T, Kilic N, Yasar MA: Effects of oxytetracycline in autologous intraperitoneal ovary transplantation in rats. Neuro Endocrinol Lett. 2003 Oct;24(5):350-4. Ovarian tissue and blood malondialdehyde (MDA) levels, superoxide dismutase (SOD) and peroxidase (GSHPx) levels were determined. |
and 1(0,0,0,1) | Details |