| Name | CYP2C19 |
|---|---|
| Synonyms | (R) limonene 6 monooxygenase; Flavoprotein linked monooxygenase; Mephenytoin 4 hydroxylase; (S) limonene 6 monooxygenase; (S) limonene 7 monooxygenase; CYP2C; CPCJ; CYP 2C… |
| Name | parathion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17079358 | Foxenberg RJ, McGarrigle BP, Knaak JB, Kostyniak PJ, Olson JR: Human hepatic cytochrome p450-specific metabolism of parathion and chlorpyrifos. Drug Metab Dispos. 2007 Feb;35(2):189-93. Epub 2006 Nov 1. CYP2B6 and CYP2C19 demonstrated low K (m) and high V (max) values for the metabolism of both model compounds, which supports their role as the primary enzymes that regulate metabolism at low-level human exposures to OPs. |
2(0,0,0,2) | Details |
| 16757081 | Mutch E, Williams FM: Diazinon, chlorpyrifos and parathion are metabolised by multiple cytochromes P450 in human liver. Toxicology. 2006 Jul 5;224(1-2):22-32. Epub 2006 Apr 26. There were significant correlations between diazoxon formation from diazinon (50 microM; 500 microM) with the three CYP3A4/5 marker reactions, while IHMP formation correlated significantly with the three CYP3A4/5 reactions, the CYP2C8 marker reaction (p <0.05) and the CYP2C19 marker (p <0.01). |
1(0,0,0,1) | Details |