Protein Information

Name beta glucuronidase
Synonyms Beta glucuronidase; Beta G1; Beta glucuronidase precursor; GUSB; MPS 7; MPS7; Beta G1s; Beta glucuronidase precursors

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
18715890 Sabbe MB, Desruelles D, Lissens W: Is beta-glucuronidase a clinical useful biomarker for an acute organophosphorus poisoning?. Hum Exp Toxicol. 2008 May;27(5):431-3.

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3439190 Foster GD, Crosby DG: Comparative metabolism of nitroaromatic compounds in freshwater, brackish water and marine decapod crustaceans. Xenobiotica. 1987 Dec;17(12):1393-404.

The unknown conjugates formed by ridgeback prawns had chromatographic properties similar to the corresponding beta-D-glucosides but were refractory to the deconjugation by alpha- or beta-glucosidase, beta-galactosidase, aryl sulphatase and beta-glucuronidase.
The metabolic pathways of p-nitroanisole, 4-nitro-m-cresol and methyl parathion in Malaysian prawns (Macrobrachium rosenbergii), ridgeback prawns (Sicyonia ingentis) and crayfish (Procambarus clarkii) were compared. 2.
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7946013 Zhu S, Liu YG: Toxicity and toxicokinetics of MeISP in isolated rat hepatocytes. . Biomed Environ Sci. 1994 Jun;7(2):169-79.


It was found that at the final concentration of 1.5 mmol/L, MeISP can (1) result in an increase of leakage of intracellular enzymes, alanine amino-transferase (ALT), lactate dehydrogenase (LDH), beta-glucuronidase (beta-GDase) and acid phosphatase (AcP) to the medium in a dose-dependent fashion; (2) give rise to obvious plasma membrane blebbing; (3) rapidly deplete the intracellular GSH and (4) almost completely inhibit the protein synthesis and gluconeogenesis from sodium pyruvate.
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3008131 Pawlowska D, Moniuszko-Jakoniuk J, Soltys M: Parathion-methyl effect on the activity of hydrolytic enzymes after single physical exercise in rats. Pol J Pharmacol Pharm. 1985 Sep-Oct;37(5):629-38.

At 1 h after pesticide administration the activity of cholinesterase (ChE) was determined in the serum, of paraoxonase--in the serum and liver, and that of beta-glucuronidase (beta-gluc)--in the serum, liver and intestine.
1(0,0,0,1) Details
3008132 Pawlowska D, Moniuszko-Jakoniuk J, Soltys M: The effect of chronic physical exercise on the activity of hydrolytic enzymes in acute poisoning with parathion-methyl in rats. Pol J Pharmacol Pharm. 1985 Sep-Oct;37(5):639-46.

The activity of cholinesterase (ChE) in the serum, of paraoxonase--in the serum and liver, and of beta-glucuronidase (beta-gluc)--in the serum, liver and intestine were determined 1 h after the treatment.
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