Protein Information

Name metallothionein (protein family or complex)
Synonyms Metallothionein; Metallothioneins

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
17982697 Calaf GM, Roy D: Human drug metabolism genes in parathion-and estrogen-treated breast cells. Int J Mol Med. 2007 Dec;20(6):875-81.

Among the genes altered by parathion in comparison to the control were CHST5, CHST6 and CHST7 (sulfotransferases); CYP2F1, CYP3A7 and CYP4F3 (CYPs); GSTP1, GSTT2 and MGST1 (GSTs); MT1X (metallothionein); TPMT (methyltransferase); UGT1A1 and UGT2B (UDP glycosyltransferases).		 13(0,0,2,3) Details
18533248 Almeida DV, Trindade GS, Geracitano LA, Barros DM, Monserrat JM, Marins LF: Initial results in the development of a reporter cell line for toxicology studies at gene expression level: activation of the electrophile-responsive element by copper and methyl parathion. Mar Environ Res. 2008 Jul;66(1):158-60. Epub 2008 Mar 8.

In order to evaluate the molecular response triggered by these pollutants, a stable cell line was produced, which carries a transgene comprised of the green fluorescent protein (GFP) reporter gene under transcriptional control of the mouse glutathione-S-transferase (gst1) electrophile-responsive element fused to the mouse metallothionein (mt1) minimal promoter.		 1(0,0,0,1) Details