| Name | AKR1C1 |
|---|---|
| Synonyms | 2 ALPHA HSD; 20 alpha hydroxysteroid dehydrogenase; 20 ALPHA HSD; AKR1C1; Aldo keto reductase C; Aldo keto reductase family 1 member C1; C9; Chlordecone reductase homolog… |
| Name | parathion |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19800895 | Hreljac I, Filipic M: Organophosphorus pesticides enhance the genotoxicity of benzo (a) pyrene by modulating its metabolism. Mutat Res. 2009 Dec 1;671(1-2):84-92. Epub 2009 Oct 2. Addition of PT or PO increased aldo-keto reductase (AKR1C1/2) levels in the presence of BaP, while cytochrome 1A (CYP1A) mRNA expression and activity were decreased. We have shown that the model OPs, methyl parathion (PT) and methyl paraoxon (PO), are genotoxic. |
1(0,0,0,1) | Details |