Protein Information

Name albumin
Synonyms ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619…

Compound Information

Name parathion
CAS

Reference List

PubMed Abstract RScore(About this table)
14700528 Silva D, Cortez CM, Cunha-Bastos J, Louro SR: Methyl parathion interaction with human and bovine serum albumin. . Toxicol Lett. 2004 Feb 28;147(1):53-61.

It was already known that parathion (ethyl parathion) exhibits a high affinity to human and bovine serum albumins.
325(4,4,4,5) Details
19800687 Silva D, Cortez-Moreira M, Cunha Bastos VL, Cunha Bastos J, Martins Cortez C: The interaction of methyl-parathion with serum and albumin of the neo-tropical fish Piaractus mesopotamicus. Ecotoxicol Environ Saf. 2010 Jan;73(1):32-7. Epub 2009 Oct 3.
177(2,2,4,7) Details
19294526 Silva D, Cortez-Moreira M, Cunha Bastos VL, Cunha Bastos J, Martins Cortez C: Spectrofluorimetric study of the interaction of methyl-parathion with fish serum albumin. Fish Physiol Biochem. 2009 Mar 18.

The interaction of methyl-parathion with the albumin of Piaractus mesopotamicus (Holmberg 1887) (= pacu), a fish species typical of Brazilian rivers, was studied and the results compared with known values for human and bovine albumin obtained in an earlier investigation.
162(2,2,2,2) Details
568924 Mourik J, de Jong LP: Binding of the organophosphates parathion and paraoxon to bovine and human serum albumin. Arch Toxicol. 1978 Oct 13;41(1):43-8.

The great difference of affinity of the serum albumins to parathion and paraoxon is discussed with respect to the fate of parathion in the body.
32(0,1,1,2) Details
6639354 Braeckman RA, Audenaert F, Willems JL, Belpaire FM, Bogaert MG: Toxicokinetics of methyl parathion and parathion in the dog after intravenous and oral administration. Arch Toxicol. 1983 Sep;54(1):71-82.

Binding of methyl parathion and parathion to dog serum, to human serum and to a solution of human albumin was determined with equilibrium dialysis.
31(0,1,1,1) Details
19575182 Noort D, Hulst AG, van Zuylen A, van Rijssel E, van der Schans MJ: Covalent binding of organophosphorothioates to albumin: a new perspective for OP-pesticide biomonitoring?. Arch Toxicol. 2009 Nov;83(11):1031-6. Epub 2009 Jul 4.

In vitro exposure levels of parathion and chlorpyrifos down to 1 microM could readily be assessed.
4(0,0,0,4) Details
7136402 Lober M, Krantz S, Herrmann I: [Production and characterization of antisera against O,O-diethyl-O-(p-nitrophenyl)-phosphate (paraoxon)]. Acta Biol Med Ger. 1982;41(5):487-96.

The highest-titre antisera were produced with conjugates containing a succinyl spacer group with a degree of derivatisation between 8 and 12 haptens per albumin molecule.
Compared to Paraoxon these antisera possessed cross reactivities with Parathion of 8.8 to 13.8%, with Methylparathion of 0.35 to 0.82%, and with Dimethoat of 0.0006 to 0.0012%.
2(0,0,0,2) Details
1621354 Benjaminov O, Hoffer E, Taitelman U, Urbach J, Brandes JM: Parathion transfer and acetylcholinesterase activity in an in-vitro perfused term human placenta. Vet Hum Toxicol. 1992 Feb;34(1):10-2.

The system consisted of maternal and fetal reservoirs in which Krebs Ringer bicarbonate buffer with heparin, albumin and glucose was circulated at a constant pH, temperature and pO2.
1(0,0,0,1) Details
933456 Lesche P, Blume U, Scheibe G, Sussmann P, Schmidt FW, Bartels M, Okonek S: [Hemoperfusion by means of encapsuled charcoal for the treatment of exogenous and endogenous intoxications]. Klin Wochenschr. 1976 Jun 1;54(11):509-16.

The method developed by Chang for using in collodion and albumin encapsuled charcoal as artificial cells for hemoperfusion has been studied in vitro.
The capacity for the absorption of more or less dialysable exogenous substances (barbiturate, Diazepam, Parathion) and an endogenous toxic metabolite (p-hydroxyphenyl acetic acid) has been examined.
1(0,0,0,1) Details
16023954 Chouteau C, Dzyadevych S, Durrieu C, Chovelon JM: A bi-enzymatic whole cell conductometric biosensor for heavy metal ions and pesticides detection in water samples. Biosens Bioelectron. 2005 Aug 15;21(2):273-81. Epub 2004 Dec 8.


For pesticides, first experiments showed that paraoxon-methyl inhibits C. vulgaris AChE contrary to parathion-methyl and carbofuran.
0(0,0,0,0) Details