Protein Information

Name phosphodiesterase
Synonyms CAMP specific phosphodiesterase variant PDE4A 10; CAMP specific phosphodiesterase variant TM3; CAMP specific phosphodiesterase; Cyclic AMP phosphodiesterase PDE4A11; Cyclic AMP specific phosphodiesterase HSPDE4A10; DPDE 2; DPDE2; PDE 4…

Compound Information

Name azobenzene
CAS diphenyldiazene

Reference List

PubMed Abstract RScore(About this table)
18404569 Liang X, Komiyama M, Asanuma H: Diastereomer separation of azobenzene-tethered oligodeoxyribonucleotides and determination of their absolute configurations by enzymatic digestion. Nucleosides Nucleotides Nucleic Acids. 2008 Apr;27(4):332-50.

We found that this modified ODN with sequence 5'-...pNpXpN...-3' (p = phosphate; N = nucleoside; X = azobenzene residue) could be digested to pX (the phosphate at the 5' side of X was left) by an over excess of Phosphodiesterase I.
31(0,1,1,1) Details
214895 Boyd H, McAfee DA, Rubin JJ: A study of cyclic nucleotide metabolism and the histology of rat liver during 3'-methyl-4-dimethylamino-azobenzene carcinogenesis. Tissue Cell. 1978;10(3):477-94.

Although phosphodiesterase activities were most elevated in the tumors, there were extremely high cyclic AMP levels in these tissues.
1(0,0,0,1) Details