| 18455858 |
Zhang SY, Ueyama J, Ito Y, Yanagiba Y, Okamura A, Kamijima M, Nakajima T: Permethrin may induce adult male mouse reproductive toxicity due to cis isomer not trans isomer. Toxicology. 2008 Jun 27;248(2-3):136-41. Epub 2008 Mar 30.
Moreover, cis-permethrin induced abnormal seminiferous tubules in testes and suppressed testicular mRNA expression levels of peripheral benzodiazepine receptor, steroidogenic acute regulatory protein, and the cytochrome P450 side-chain cleavage enzyme. |
81(1,1,1,1) |
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| 17463061 |
Zhang SY, Ito Y, Yamanoshita O, Yanagiba Y, Kobayashi M, Taya K, Li C, Okamura A, Miyata M, Ueyama J, Lee CH, Kamijima M, Nakajima T: Permethrin may disrupt testosterone biosynthesis via mitochondrial membrane damage of Leydig cells in adult male mouse. Endocrinology. 2007 Aug;148(8):3941-9. Epub 2007 Apr 26.
Moreover, cis-permethrin exposure significantly diminished the testicular mitochondrial mRNA expression levels of peripheral benzodiazepine receptor (PBR), steroidogenic acute regulatory protein (StAR), and cytochrome P450 side-chain cleavage (P450scc) and enzyme and protein expression levels of StAR and P450scc. |
31(0,1,1,1) |
Details |