Protein Information

Name a C1
Synonyms A C1; H REV107; HRAS like suppressor; HRASLS; HRASLS 1; HRASLS1; HSD28; HRAS like suppressors

Compound Information

Name phosphine
CAS phosphine

Reference List

PubMed Abstract RScore(About this table)
17474745 Ebran JP, Hansen AL, Gogsig TM, Skrydstrup T: Studies on the Heck reaction with alkenyl phosphates: can the 1,2-migration be controlled? Scope and limitations. J Am Chem Soc. 2007 May 30;129(21):6931-42. Epub 2007 May 3.

The extent of the 1,2-migration was dependent on the C1-substituent where best results were noted for substrates possessing a C1-alkyl quaternary carbon.
Hence, with certain members of this class of alkenyl phosphates either the migrated or nonmigrated Heck products may be preferentially synthesized by selection of the phosphine ligand.
1(0,0,0,1) Details
17064049 Uozumi Y, Suzuka T: pi-Allylic C1-substitution in water with nitromethane using amphiphilic resin-supported palladium complexes. J Org Chem. 2006 Oct 27;71(22):8644-6.

Nitromethane was safely applied as a C1 nucleophile for palladium-catalyzed pi-allylic substitution in water with amphiphilic PS-PEG resin-supported phosphine-palladium complexes.
31(0,1,1,1) Details